Reinbach H C, Smeets A, Martinussen T, Møller P, Westerterp-Plantenga M S
Department of Food Science, University of Copenhagen, Rolighedsvej 30, Frederiksberg C, Denmark.
Clin Nutr. 2009 Jun;28(3):260-5. doi: 10.1016/j.clnu.2009.01.010. Epub 2009 Apr 3.
BACKGROUND & AIMS: Bioactive ingredients have been shown to reduce appetite and energy intake. The magnitude of these effects might depend on energy balance why it was investigated how capsaicin, green tea, CH-19 sweet pepper as well as green tea and capsaicin affect appetite and energy intake during respectively negative and positive energy balance.
27 subjects were randomized to three weeks of negative and three weeks of positive energy balance during which capsaicin, green tea, CH-19 sweet pepper, capsaicin+green tea or placebo was ingested on ten separate test days while the effects on appetite, energy intake, body weight and heart rate were assessed.
CH-19 sweet pepper and a combination of capsaicin and green tea reduced energy intake during positive energy balance. Capsaicin and green tea suppressed hunger and increased satiety more during negative than during positive energy balance.
Bioactive ingredients had energy intake reducing effects when used in combinations and in positive energy balance. Energy balance did not affect possible treatment induced energy intake, but did affect appetite by supporting negative energy balance. Bioactive ingredients may therefore be helpful in reducing energy intake and might support weight loss periods by relatively sustaining satiety and suppressing hunger.
生物活性成分已被证明可降低食欲和能量摄入。这些作用的程度可能取决于能量平衡，因此研究了辣椒素、绿茶、CH-19甜椒以及绿茶和辣椒素在负能量平衡和正能量平衡期间分别如何影响食欲和能量摄入。
27名受试者被随机分为三组，分别进行为期三周的负能量平衡期和为期三周的正能量平衡期。在十个不同的测试日期间，受试者分别摄入辣椒素、绿茶、CH-19甜椒、辣椒素+绿茶或安慰剂，同时评估其对食欲、能量摄入、体重和心率的影响。
CH-19甜椒以及辣椒素和绿茶的组合在正能量平衡期间可降低能量摄入。辣椒素和绿茶在负能量平衡期间比在正能量平衡期间更能抑制饥饿感并增加饱腹感。
生物活性成分在组合使用以及处于正能量平衡时具有降低能量摄入的作用。能量平衡并未影响可能由治疗引起的能量摄入，但通过支持负能量平衡对食欲产生了影响。因此，生物活性成分可能有助于减少能量摄入，并可能通过相对维持饱腹感和抑制饥饿感来辅助减肥阶段。
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