Department of Human Biology, Nutrim, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
Int J Obes (Lond). 2010 Apr;34(4):659-69. doi: 10.1038/ijo.2009.299. Epub 2010 Feb 9.
The global prevalence of obesity has increased considerably in the last decade. Tools for obesity management, including consumption of caffeine, capsaicin and different teas such as green, white and oolong tea, have been proposed as strategies for weight loss and weight maintenance, as they may increase energy expenditure (4-5%), fat oxidation (10-16%) and have been proposed to counteract the decrease in metabolic rate that is present during weight loss. Daily increases in thermogenesis of approximately 300-400 kJ can eventually lead to substantial weight loss. However, it becomes clearer that certain conditions have to be met before thermogenic ingredients yield an effect, as intra-variability with respect to body weight regulation has been shown between subjects. Furthermore, the sympathetic nervous system is involved in the regulation of lipolysis, and the sympathetic innervation of white adipose tissue may have an important role in the regulation of total body fat in general. Taken together, these functional ingredients have the potential to produce significant effects on metabolic targets such as satiety, thermogenesis and fat oxidation. A significant clinical outcome may sometimes appear straightforward and may also depend very strongly on full compliance of subjects. Nevertheless, thermogenic ingredients may be considered as functional agents that could help in preventing a positive energy balance and obesity.
在过去的十年中，肥胖在全球范围内的患病率显著增加。人们提出了一些肥胖管理工具，包括摄入咖啡因、辣椒素和不同的茶，如绿茶、白茶和乌龙茶，作为减肥和保持体重的策略，因为它们可以增加能量消耗（4-5%），促进脂肪氧化（10-16%），并被提议对抗减肥过程中代谢率下降的问题。每天增加的热量大约为 300-400 kJ，最终可能导致显著的体重减轻。然而，越来越明显的是，在热生成成分产生效果之前，必须满足某些条件，因为已经表明在个体之间存在体重调节的个体内可变性。此外，交感神经系统参与脂肪分解的调节，白色脂肪组织的交感神经支配可能在调节总体体脂肪方面起着重要作用。总之，这些功能性成分有可能对饱腹感、产热和脂肪氧化等代谢目标产生显著影响。有时，显著的临床效果似乎很直接，但也非常强烈地依赖于受试者的完全依从性。然而，热生成成分可以被认为是功能性药物，可以帮助预防正的能量平衡和肥胖。
