Pujol R M, Matias-Guíu X, Garcìa-Patos V, de Moragas J M
Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Clin Exp Dermatol. 1991 May;16(3):199-201. doi: 10.1111/j.1365-2230.1991.tb00346.x.
A 21-year-old man presented with an erythematous pruritic plaque on the right parietal scalp of 2 years' evolution. Physical examination disclosed multiple bundles of hairs emerging from single dilated follicular openings. The disorder followed a relapsing and progressive course, in spite of several topical and systemic treatments. New tufts of hairs appeared in previously non-involved areas only after inflammatory changes occurred. The clinicopathological features, aetiological mechanisms and management of tufted-hair folliculitis are discussed. Tufted-hair folliculitis (THF) is a localized, inflammatory and exudative disease of the scalp characterized by a tufted appearance of the scalp hair, that may result in permanent and irreversible scarring alopecia. This condition was initially described by Smith and Sanderson in 1978 who coined the term THF to illustrate the phenomenon of multiple hairs emerging from single follicular openings. Only nine additional cases of THF have been reported elsewhere. We present herein a patient with recurrent and progressive THF resistant to several therapeutic strategies.
一名21岁男性，右侧顶叶头皮出现红斑瘙痒性斑块，病程已达2年。体格检查发现多个毛囊开口扩张，有多束毛发从中长出。尽管接受了多种局部和全身治疗，病情仍呈复发和进展性。只有在出现炎症变化后，先前未受累的区域才会出现新的毛发簇。本文讨论了簇状毛发毛囊炎的临床病理特征、病因机制及治疗方法。簇状毛发毛囊炎（THF）是一种头皮局部性、炎症性和渗出性疾病，其特征为头皮毛发呈簇状外观，可导致永久性和不可逆性瘢痕性脱发。这种情况最初由史密斯和桑德森于1978年描述，他们创造了“THF”一词来描述从单个毛囊开口长出多根毛发的现象。其他地方仅另外报道了9例THF病例。我们在此报告一名对多种治疗策略均耐药的复发性、进展性THF患者。
