Mutinelli Franco, Carminato Antonio, Bozzato Elisa, Marchioro Wendy, Trevisan Laura, Vascellari Marta
Istituto Zooprofilattico Sperimentale delle Venezie, Histopathology Department, Viale dell'Universita', Legnaro (Padova), Italy.
J Vet Med Sci. 2009 Mar;71(3):367-70. doi: 10.1292/jvms.71.367.
Teratomas are histologically complex tumors arising from germ cells of two or three embryonic layers either in the gonads or occasionally from germ cells that mistakenly migrated to ectopic sites. A case of retroperitoneal teratoma in a regularly slaughtered 4-month-old, male domestic rabbit is reported. A pale reddish, 3 x 4 cm, fibrous mass was detected, loosely connected to the parietal wall in the retroperitoneal region cranial to the kidney. Histologically, the neoplasm contained tissues from ectodermal, endodermal and mesodermal germ layers: nerves and neurons simulating ganglia, cysts lined by squamous epithelium containing keratin and hair, skin adnexa; respiratory glandular epithelium, serous and salivary glands; collagenous connective tissue, muscle fibers, mature cartilage and bone, bone marrow, teeth and fat. To the authors' knowledge this is the first report of a retroperitoneal teratoma in the rabbit.
畸胎瘤是组织学上复杂的肿瘤,起源于性腺中两个或三个胚胎层的生殖细胞,偶尔也起源于错误迁移到异位部位的生殖细胞。本文报道了一例在常规屠宰的4月龄雄性家兔中发现的腹膜后畸胎瘤。在肾脏上方的腹膜后区域发现了一个淡红色、3×4厘米的纤维性肿块,与腹壁疏松相连。组织学检查显示,该肿瘤包含来自外胚层、内胚层和中胚层生殖层的组织:模拟神经节的神经和神经元、内衬含有角蛋白和毛发的鳞状上皮的囊肿、皮肤附属器;呼吸腺上皮、浆液腺和唾液腺;胶原结缔组织、肌纤维、成熟软骨和骨、骨髓、牙齿和脂肪。据作者所知,这是兔腹膜后畸胎瘤的首例报告。