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家兔(穴兔)的腹膜后畸胎瘤。

Retroperitoneal teratoma in a domestic rabbit (Oryctolagus cuniculus).

作者信息

Mutinelli Franco, Carminato Antonio, Bozzato Elisa, Marchioro Wendy, Trevisan Laura, Vascellari Marta

机构信息

Istituto Zooprofilattico Sperimentale delle Venezie, Histopathology Department, Viale dell'Universita', Legnaro (Padova), Italy.

出版信息

J Vet Med Sci. 2009 Mar;71(3):367-70. doi: 10.1292/jvms.71.367.

Abstract

Teratomas are histologically complex tumors arising from germ cells of two or three embryonic layers either in the gonads or occasionally from germ cells that mistakenly migrated to ectopic sites. A case of retroperitoneal teratoma in a regularly slaughtered 4-month-old, male domestic rabbit is reported. A pale reddish, 3 x 4 cm, fibrous mass was detected, loosely connected to the parietal wall in the retroperitoneal region cranial to the kidney. Histologically, the neoplasm contained tissues from ectodermal, endodermal and mesodermal germ layers: nerves and neurons simulating ganglia, cysts lined by squamous epithelium containing keratin and hair, skin adnexa; respiratory glandular epithelium, serous and salivary glands; collagenous connective tissue, muscle fibers, mature cartilage and bone, bone marrow, teeth and fat. To the authors' knowledge this is the first report of a retroperitoneal teratoma in the rabbit.

摘要

畸胎瘤是组织学上复杂的肿瘤,起源于性腺中两个或三个胚胎层的生殖细胞,偶尔也起源于错误迁移到异位部位的生殖细胞。本文报道了一例在常规屠宰的4月龄雄性家兔中发现的腹膜后畸胎瘤。在肾脏上方的腹膜后区域发现了一个淡红色、3×4厘米的纤维性肿块,与腹壁疏松相连。组织学检查显示,该肿瘤包含来自外胚层、内胚层和中胚层生殖层的组织:模拟神经节的神经和神经元、内衬含有角蛋白和毛发的鳞状上皮的囊肿、皮肤附属器;呼吸腺上皮、浆液腺和唾液腺;胶原结缔组织、肌纤维、成熟软骨和骨、骨髓、牙齿和脂肪。据作者所知,这是兔腹膜后畸胎瘤的首例报告。

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