Khoroshilova I P
Arkh Patol. 1977;39(2):23-9.
Morphogenesis of adenovirus (epidemic keratoconjunctivitis) and chlamydia (paratrachoma) infections was studied on the material consisting of scrapings of the conjunctiva and biopsy specimens taken from 410 patients, by histological, cytological, histo- and cytochemical electron-microscopic and immunohistochemical methods. The investigations conducted showed that the morphogenesis of adenovirus and chlamydia infection of the conjunctiva was underlaid by a complex of pathological disorders including changes in the epithelium, where the cytopathogenic effect of the pathogene was realized, and changes in the conjunctiva tissue proper, the latter being transformed in these infections into the organ of immunogenesis.
采用组织学、细胞学、组织化学、细胞化学、电子显微镜及免疫组织化学方法,对410例患者结膜刮片和活检标本进行研究,以观察腺病毒(流行性角结膜炎)和衣原体(副沙眼)感染的形态发生。研究结果表明,结膜腺病毒和衣原体感染的形态发生是由一系列病理紊乱所构成,这些紊乱包括上皮细胞的变化(病原体的细胞致病作用在此得以体现)以及结膜组织本身的变化,在这些感染中结膜组织转变为免疫发生器官。