Furnée Edgar J B, Draaisma Werner A, Broeders Ivo A M J, Gooszen Hein G
Department of Surgery, H.P. G04.228, University Medical Centre Utrecht, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
J Gastrointest Surg. 2009 Aug;13(8):1539-49. doi: 10.1007/s11605-009-0873-z. Epub 2009 Apr 4.
Outcome and morbidity of redo antireflux surgery are suggested to be less satisfactory than those of primary surgery. Studies reporting on redo surgery, however, are usually much smaller than those of primary surgery. The aim of this study was to summarize the currently available literature on redo antireflux surgery.
A structured literature search was performed in the electronic databases of MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials.
A total of 81 studies met the inclusion criteria. The study design was prospective in 29, retrospective in 15, and not reported in 37 studies. In these studies, 4,584 reoperations in 4,509 patients are reported. Recurrent reflux and dysphagia were the most frequent indications; intraoperative complications occurred in 21.4% and postoperative complications in 15.6%, with an overall mortality rate of 0.9%. The conversion rate in laparoscopic surgery was 8.7%. Mean(+/-SEM) duration of surgery was 177.4 +/- 10.3 min and mean hospital stay was 5.5 +/- 0.5 days. Symptomatic outcome was successful in 81.1% and was equal in the laparoscopic and conventional approach. Objective outcome was obtained in 24 studies (29.6%) and success was reported in 78.3%, with a slightly higher success rate in case of laparoscopy than with open surgery (85.8% vs. 78.0%).
This systematic review on redo antireflux surgery has confirmed that morbidity and mortality after redo surgery is higher than after primary surgery and symptomatic and objective outcome are less satisfactory. Data on objective results were scarce and consistency with regard to reporting outcome is necessary.
再次抗反流手术的结果和发病率被认为不如初次手术。然而,关于再次手术的研究通常比初次手术的研究规模小得多。本研究的目的是总结目前关于再次抗反流手术的现有文献。
在MEDLINE、EMBASE和Cochrane对照试验中央注册库的电子数据库中进行了结构化文献检索。
共有81项研究符合纳入标准。研究设计为前瞻性的有29项,回顾性的有15项,37项研究未报告研究设计。在这些研究中,报告了4509例患者的4584例再次手术。复发性反流和吞咽困难是最常见的指征;术中并发症发生率为21.4%,术后并发症发生率为15.6%,总死亡率为0.9%。腹腔镜手术的中转开腹率为8.7%。平均(±标准误)手术时间为177.4±10.3分钟,平均住院时间为5.5±0.5天。症状性结局成功率为81.1%,腹腔镜手术和传统手术的成功率相当。24项研究(29.6%)获得了客观结局,报告的成功率为78.3%,腹腔镜手术的成功率略高于开放手术(85.8%对78.0%)。
这项关于再次抗反流手术的系统评价证实,再次手术后的发病率和死亡率高于初次手术,症状性和客观结局不太令人满意。关于客观结果的数据稀少,有必要在报告结局方面保持一致性。