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[一例由新型隐球菌引起的急性小脑脑炎]

[A case of acute cerebellar encephalitis due to Cryptococcus neoformans].

作者信息

Watanabe Y, Shikano A, Ohba M, Ohkubo M, Niwa T

机构信息

Department of Internal Medicine, Ohgaki Municipal Hospital.

出版信息

Rinsho Shinkeigaku. 1991 Jun;31(6):658-61.

PMID:1934783
Abstract

A case of acute cryptococcal cerebellar encephalitis with CT enhancement confined to the cerebellum is reported. A 46-year-old man with hepatoma was admitted with chief complaints of headache, fever and dizziness. On admission, cerebellar signs (disturbance of finger-to-nose test and of heel-to-knee test, intention tremor, and truncal ataxia) were neurologically noted. However, there were no brainstem signs. Head CT showed swelling and enhancement of the cerebellar cortex and dilatation of the cerebral ventriculi. Cryptococcus neoformans was detected in a culture of the patient's CSF. Clinical symptoms and signs, and enhancement of the cerebellum on CT gradually diminished after administration of anti-fungal drugs, and CSF became negative for cryptococcal antigen 6 months after admission.

摘要

报告了一例急性隐球菌性小脑脑炎,CT增强仅局限于小脑。一名46岁肝癌男性因头痛、发热和头晕为主诉入院。入院时,神经系统检查发现有小脑体征(指鼻试验和跟膝试验障碍、意向性震颤和躯干共济失调)。然而,没有脑干体征。头部CT显示小脑皮质肿胀、强化及脑室扩张。患者脑脊液培养检测到新型隐球菌。给予抗真菌药物后,临床症状和体征以及CT上小脑的强化逐渐减轻,入院6个月后脑脊液隐球菌抗原转阴。

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