Muramatsu Yoko, Sugino Keishi, Kikuchi Naoshi, Sano Go, Isobe Kazutoshi, Takai Yujiro, Takagi Keigo, Shibuya Kazutoshi, Homma Sakae
Department of Respiratory Medicine, Toho University School of Medicine.
Nihon Kokyuki Gakkai Zasshi. 2009 Mar;47(3):237-41.
A 73-year-old woman was admitted to our hospital to evaluate mediastinal lymphadenopathy found on a chest CT scan. She had undergone mammoplasty with silicone augmentation 50 years previously and had the implants removed 5 years previously. Biopsied specimens of a mediastinal lymph node under video-assisted thoracic surgery (VATS) revealed multiple hyalinized non-caseating epithelioid cell granulomas and multinucleated giant cells and foamy macrophages containing some vacuoles. According to these clinicopathological findings, we diagnosed human adjuvant disease which developed after mammoplasty with silicone augmentation. In cases of mammoplasty, we should pay attention to the complication of chronic thoracic disorder as a human adjuvant disease.
一名73岁女性因胸部CT扫描发现纵隔淋巴结肿大而入住我院。她50年前接受了硅胶隆胸手术，5年前取出了植入物。电视辅助胸腔镜手术（VATS）下纵隔淋巴结活检标本显示多个玻璃样变的非干酪样上皮样细胞肉芽肿、多核巨细胞以及含有一些空泡的泡沫巨噬细胞。根据这些临床病理表现，我们诊断为硅胶隆胸术后发生的人类佐剂病。在隆胸手术病例中，我们应注意作为人类佐剂病的慢性胸部疾病并发症。
