Lautenschlager I, Häyry P
Fourth Department of Surgery, University of Helsinki, Finland.
Clin Lab Med. 1991 Sep;11(3):653-70.
A variety of methods have been proposed to monitor organ allograft rejection using blood, urine, or body fluids. None of these methods, however, have fulfilled the expectations. Biopsy histology has remained a gold standard in the evaluation of in situ events in the graft. Fine needle aspiration biopsy, although invasive, is less traumatic than needle or open biopsy, particularly during the immediate postoperative course when the frequency of acute cellular rejection is the highest. These histologic and cytologic methods should always be used in combination with other methods of clinical diagnostic tests, particularly infection diagnostics.
已经提出了多种使用血液、尿液或体液来监测器官同种异体移植排斥反应的方法。然而，这些方法都没有达到预期。活检组织学仍然是评估移植物原位事件的金标准。细针穿刺活检虽然具有侵入性，但比针吸活检或开放活检的创伤性小，特别是在术后即刻急性细胞排斥反应频率最高的时候。这些组织学和细胞学方法应始终与其他临床诊断测试方法结合使用，尤其是感染诊断方法。
