Dillon Erin R, Bjornson Kristie F, Jaffe Kenneth M, Hall Judith G, Song Kit
University of Washington Medical School, Seattle, WA, USA.
J Pediatr Orthop. 2009 Mar;29(2):214-7. doi: 10.1097/BPO.0b013e3181990214.
Arthrogryposis is characterized by multiple congenital joint contractures that affect ambulation. This study compared ambulatory activity of subjects with the 2 most common forms of arthrogryposis and a control group of typically developing youth.
This is a cross-sectional, cohort study. Thirteen ambulatory subjects with amyoplasia or distal arthrogryposis and 13 age- and sex-matched controls wore the StepWatch3 Activity Monitor on their ankles for 7 days. The daily frequency, duration, and intensity of ambulatory activity were measured. The parents of the subjects also completed Activities Scale for Kids, Performance-38 questionnaires to compare parent-reported activity levels with StepWatch3 Activity Monitor measurements.
The mean ages of the subject and control groups were 10.83 and 10.95 years, respectively, with 8 males and 5 females in each group. Subjects as compared with controls took significantly fewer steps, 5668+/-1134 versus 7685+/-1164, respectively (P=0.02) and spent significantly less of their active time at high step rates, 8% versus 13% (P=0.05). The average Activities Scale for Kids, Performance summary scores for subjects (76.8+/-18.9) were significantly lower than controls (90.6+/-7.2) (P=0.003).
We have been able to quantify the activity levels of children with amyoplasia and distal arthrogryposis relative to that of age- and sex-matched typically developing youth. Youth with arthrogryposis took significantly fewer steps, spent less time at high activity levels, and had significantly lower parental report of ambulatory and physical activity than controls.
Cross-sectional comparison study, level II.
先天性多发性关节挛缩症的特征是出现影响行走的多个先天性关节挛缩。本研究比较了患有两种最常见形式先天性多发性关节挛缩症的受试者与一组发育正常的青年对照组的行走活动情况。
这是一项横断面队列研究。13名患有缺肢型或远端关节挛缩型先天性多发性关节挛缩症的可独立行走受试者以及13名年龄和性别匹配的对照组人员在脚踝处佩戴StepWatch3活动监测仪7天。测量每日行走活动的频率、持续时间和强度。受试者的父母还完成了儿童活动量表、Performance - 38问卷，以比较父母报告的活动水平与StepWatch3活动监测仪的测量结果。
受试者组和对照组的平均年龄分别为10.83岁和10.95岁，每组均有8名男性和5名女性。与对照组相比，受试者的步数明显更少，分别为5668±1134步和7685±1164步（P = 0.02），且在高步频下的活跃时间明显更短，分别为8%和13%（P = 0.05）。受试者的儿童活动量表平均Performance总结得分（76.8±18.9）明显低于对照组（90.6±7.2）（P = 0.003）。
我们已经能够量化患有缺肢型和远端关节挛缩型先天性多发性关节挛缩症的儿童相对于年龄和性别匹配的发育正常青年的活动水平。患有先天性多发性关节挛缩症的青年步数明显更少，在高活动水平下花费的时间更少，并且父母报告的其行走和身体活动水平明显低于对照组。
横断面比较研究，二级。
