Hampl M
Frauenklinik der Universität Düsseldorf.
Dtsch Med Wochenschr. 2009 Apr;134 Suppl 2:S95-9. doi: 10.1055/s-0029-1220218. Epub 2009 Apr 7.
Most cervical cancers are caused by human papillomavirus (HPV) genotypes 16 or 18, while almost all the anogenital warts are related to HPV 6 and 11. In placebo-controlled trials, a vaccine against HPV (6, 11, 16, 18) almost completely prevented infections and associated clinical lesions in primarily not infected women. Furthermore, new data demonstrate that sexually active women, as well as those with prior infection, also benefit from the vaccine. These results suggest that a general vaccination programme for sexually active women will be beneficial.
大多数宫颈癌由人乳头瘤病毒(HPV)16型或18型引起,而几乎所有的肛门生殖器疣都与HPV 6型和11型有关。在安慰剂对照试验中,一种针对HPV(6、11、16、18型)的疫苗几乎完全预防了主要未感染女性的感染及相关临床病变。此外,新数据表明,性活跃女性以及既往有感染的女性也能从该疫苗中获益。这些结果表明,为性活跃女性开展的常规疫苗接种计划将有益处。