细胞学和流式细胞术用于识别两名儿童中伪装成甲状腺结节的异位胸腺组织。
Cytology and flow cytometry to identify ectopic thymic tissue masquerading as a thyroid nodule in two children.
作者信息
Aguayo-Figueroa Lourdes, Golightly Marc G, Hu Youjun, Cohen Harris L, Wilson Thomas A
机构信息
Division of Pediatric Endocrinology, Department of Pediatrics, State University of New York, Stony Brook, New York 11794-8111, USA.
出版信息
Thyroid. 2009 Apr;19(4):403-6. doi: 10.1089/thy.2008.0201.
BACKGROUND
Clinically unapparent thyroid nodules in children pose a significant problem in differential diagnosis and management. Ectopic thymic tissue in the thyroid gland is rare, but may masquerade as a thyroid nodule. This paper demonstrates the utility of flow cytometry as an adjunct to cytology by fine needle aspiration in diagnosing ectopic thymic tissue in the thyroid gland.
SUMMARY
By demonstration of T lymphocytes maturing along two cell lineages and the absence of markers for malignant lesions, fine-needle aspiration, cytology, and flow cytometry were used to identify ectopic thymic tissue masquerading as a thyroid nodule in two children.
CONCLUSION
Use of this technique prevented surgical intervention that otherwise would have been necessary to obtain an accurate diagnosis of these thyroid nodules.
背景
儿童临床隐匿性甲状腺结节在鉴别诊断和处理方面是一个重大问题。甲状腺内的异位胸腺组织罕见，但可能伪装成甲状腺结节。本文通过细针穿刺抽吸术联合流式细胞术诊断甲状腺内异位胸腺组织，展示了流式细胞术作为细胞学辅助手段的实用性。
总结
通过显示T淋巴细胞沿两个细胞谱系成熟以及缺乏恶性病变标志物，采用细针穿刺抽吸术、细胞学检查和流式细胞术来识别两名儿童中伪装成甲状腺结节的异位胸腺组织。
结论
使用该技术避免了为准确诊断这些甲状腺结节而原本需要进行的手术干预。
Zotero 插件