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异位甲状腺内胸腺伴甲状腺内甲状旁腺作为成人孤立性甲状腺结节的一个病因

Ectopic intrathyroidal thymus accompanied by intrathyroidal parathyroid as a cause of a solitary thyroid nodule in adult.

作者信息

Kim Aeri, Kang Su Hwan, Bae Young Kyung

机构信息

Department of Pathology, Daegu Fatima Hospital Daegu, South Korea.

Department of Surgery, Yeungnam University College of Medicine Daegu, South Korea.

出版信息

Int J Clin Exp Pathol. 2014 Aug 15;7(9):6375-8. eCollection 2014.

Abstract

Ectopic intrathyroidal thymic tissue can form a mass lesion within the thyroid gland and has rarely been reported in children. We report a case of intrathyroidal thymus accompanied by an intrathyroidal parathyroid gland in a 29-year-old woman who visited our hospital due to right neck mass diagnosed as metastatic papillary carcinoma by aspiration cytology in an outside hospital. She had a history of right thyroidectomy due to papillary thyroid carcinoma three years ago. Ultrasonographic examination of the left thyroid gland showed a well-defined hyperechoic nodule, which did not show change in size compared with the previous study. She underwent complete thyroidectomy with right neck dissection. Grossly, the left thyroid had a well demarcated pale yellow nodule measuring 0.9 cm in diameter. On microscopic examination, the nodule was composed of mature fat tissue, ectopic thymic tissue with Hassall's corpuscles, and an intrathyroidal parathyroid gland. This is an exceedingly rare case of ectopic intrathyroidal thymus with intrathyroidal parathyroid gland, in an adult.

摘要

异位甲状腺内胸腺组织可在甲状腺内形成肿块性病变,在儿童中鲜有报道。我们报告一例29岁女性甲状腺内胸腺伴甲状腺内甲状旁腺的病例,该患者因右颈部肿块就诊于我院,在外院经细针穿刺细胞学检查诊断为转移性乳头状癌。她三年前因乳头状甲状腺癌接受过右侧甲状腺切除术。对左侧甲状腺的超声检查显示一个边界清晰的高回声结节,与之前的检查相比大小未发生变化。她接受了全甲状腺切除术及右侧颈部清扫术。大体检查显示,左侧甲状腺有一个边界清晰的淡黄色结节,直径0.9厘米。显微镜检查发现,该结节由成熟脂肪组织、含有哈氏小体的异位胸腺组织和甲状腺内甲状旁腺组成。这是一例极为罕见的成人甲状腺内异位胸腺伴甲状腺内甲状旁腺的病例。

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