Einstein Andrew J
Department of Medicine, Cardiology Division, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.
JACC Cardiovasc Imaging. 2009 Mar;2(3):369-71. doi: 10.1016/j.jcmg.2008.10.008.
Approximately 9 million nuclear cardiology studies performed each year in the U.S. use technetium-99m, which is produced from the decay of molybdenum-99. The fragility of the worldwide technetium-99m supply chain has been underscored by current shortages caused by an unplanned shutdown of Europe's largest reactor. The majority of the U.S. supply derives from a reactor in Canada that is nearing the end of its lifespan and whose planned replacements have been cancelled recently. In this article, the clinical importance of technetium-99m and our tenuous dependence on the foreign supply of molybdenum are addressed, along with potential measures that may be taken to ensure that America's supply chain remains unbroken.
在美国,每年大约有900万例核心脏病学研究使用由钼-99衰变产生的锝-99m。欧洲最大反应堆的意外关闭导致目前的短缺,凸显了全球锝-99m供应链的脆弱性。美国大部分供应来自加拿大的一座反应堆,该反应堆已接近使用寿命末期,且其计划中的替代反应堆最近已被取消。本文探讨了锝-99m的临床重要性以及我们对国外钼供应的脆弱依赖,同时还讨论了为确保美国供应链不受影响可能采取的措施。