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使用外用5-氨基酮戊酸光动力疗法(ALA-PDT)治疗皮肤癌及癌前病变——单家医院的经验

Treatment of skin cancer and pre-cancer using topical ALA-PDT--a single hospital experience.

作者信息

Wang Xiu-Li, Wang Hong-Wei, Guo Min-Xia, Xu Shi-Zheng

机构信息

Shanghai Skin Diseases & STD Hospital, Shanghai 200050, PR China.

出版信息

Photodiagnosis Photodyn Ther. 2008 Jun;5(2):127-33. doi: 10.1016/j.pdpdt.2008.05.003. Epub 2008 Jun 27.

DOI:10.1016/j.pdpdt.2008.05.003
PMID:19356643
Abstract

Our hospital (Shanghai Skin Diseases & STD Hospital) started to study 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) in 1996. So far, we have treated 76 cases of skin cancer and pre-cancer using topical ALA-PDT. They included squamous cell carcinoma (SCC), basal cell carcinoma (BCC), Bowen's disease (BD), mammary and extramammary Paget disease, actinic keratosis (AK) and erythroplasia of Queyrat. In this overview article, we would like to present several representative cases and discuss our experience.

摘要

我院(上海市皮肤病性病医院)于1996年开始研究5-氨基酮戊酸介导的光动力疗法(ALA-PDT)。迄今为止,我们已使用外用ALA-PDT治疗了76例皮肤癌及癌前病变患者。这些病变包括鳞状细胞癌(SCC)、基底细胞癌(BCC)、鲍温病(BD)、乳腺及乳腺外佩吉特病、光化性角化病(AK)和Queyrat增殖性红斑。在这篇综述文章中,我们将展示几例具有代表性的病例并讨论我们的经验。

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