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慢性致残性髂股静脉阻塞性病变的血管内治疗:长期结果

Endovascular management of chronic disabling ilio-caval obstructive lesions: long-term results.

作者信息

Hartung O, Loundou A D, Barthelemy P, Arnoux D, Boufi M, Alimi Y S

机构信息

Department of Vascular Surgery, CHU Nord, Marseille, France.

出版信息

Eur J Vasc Endovasc Surg. 2009 Jul;38(1):118-24. doi: 10.1016/j.ejvs.2009.03.004. Epub 2009 Apr 8.

Abstract

OBJECTIVE

To report the long-term results of stenting for chronic ilio-caval obstructive lesions.

MATERIAL AND METHODS

From January 1996 to January 2008, 89 patients (72 women, 17 men; median age 43 years) were admitted for endovascular treatment of chronic disabling non-malignant obstructive ilio-caval lesions. Patients were classified as C2 in 15 cases, C3 in 59, C4 in seven, C5 in two and C6 in six. Median preoperative venous disability score (VDS) and venous clinical severity score (VCSS) were 2 and 9, respectively. Aetiology was primary in 52 patients, secondary in 35 and congenital in two. Lesions were bilateral in seven cases, eight patients had inferior vena cava (IVC) involvement and 18 had common femoral vein (CFV) obstructive lesions. Complete occlusion was found in 30 cases.

RESULTS

Technical success was achieved in 98%. The median hospital stay was 2 days. During a median follow-up of 38 months (range: 1-144 months), one patient died and five cases of thromboses occurred. Iterative stenting was performed for restenosis in six cases. Primary, assisted-primary and secondary patency rates, in terms of intention to treat, were 83%, 89% and 93%, respectively, at 3 and 10 years, with a median VDS of 1. Univariate analysis found that significant factors affecting patency were CFV involvement for primary patency and history of deep venous thrombosis (DVT) and CFV involvement for secondary patency. The last 46 patients had statistically more severe lesions than the first 43 (higher VDS, more secondary lesions, more occlusions, more stented segments, higher length of stented vein), and in spite of which patency rates are not different.

CONCLUSION

Endovenous angioplasty, combined with stenting, is a sure, safe, effective and very minimally invasive technique which provides good long-term patency rates. Currently, it is recognised as the technique of choice for the treatment of ilio-caval obstructive lesions. Surgery should be proposed only in case of failure.

摘要

目的

报告慢性髂股静脉阻塞性病变支架置入术的长期结果。

材料与方法

1996年1月至2008年1月,89例患者(72例女性,17例男性;中位年龄43岁)因慢性致残性非恶性髂股静脉阻塞性病变入院接受血管内治疗。患者分类为C2级15例,C3级59例,C4级7例,C5级2例,C6级6例。术前静脉功能障碍评分(VDS)和静脉临床严重程度评分(VCSS)中位数分别为2分和9分。病因原发性52例,继发性35例,先天性2例。病变双侧7例,8例累及下腔静脉(IVC),18例累及股总静脉(CFV)阻塞性病变。发现30例完全闭塞。

结果

技术成功率为98%。中位住院时间为2天。中位随访38个月(范围:1 - 144个月),1例患者死亡,发生5例血栓形成。6例因再狭窄进行了反复支架置入术。意向性治疗方面,3年和10年的原发性、辅助原发性和继发性通畅率分别为83%、89%和93%,VDS中位数为1分。单因素分析发现,影响通畅的显著因素为原发性通畅的CFV累及、深静脉血栓形成(DVT)病史以及继发性通畅的CFV累及。最后46例患者的病变在统计学上比前43例更严重(VDS更高、继发性病变更多、闭塞更多、支架置入节段更多、支架置入静脉长度更长),尽管如此,通畅率并无差异。

结论

静脉血管成形术联合支架置入术是一种可靠、安全、有效且微创性极小的技术,可提供良好的长期通畅率。目前,它被认为是治疗髂股静脉阻塞性病变的首选技术。仅在失败的情况下才应考虑手术。

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