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Second-generation HIV microbicides: continued development of griffithsin.

作者信息

Zeitlin Larry, Pauly Michael, Whaley Kevin J

机构信息

Mapp Biopharmaceutical, Inc., 6160 Lusk Boulevard, C105, San Diego, CA 92121, USA.

出版信息

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6029-30. doi: 10.1073/pnas.0902239106. Epub 2009 Apr 8.

Abstract
摘要

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本文引用的文献

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Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component.
Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6099-104. doi: 10.1073/pnas.0901506106. Epub 2009 Mar 30.
3
Whither or wither microbicides?
Science. 2008 Jul 25;321(5888):532-4. doi: 10.1126/science.1160355.
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Plant-produced idiotype vaccines for the treatment of non-Hodgkin's lymphoma: safety and immunogenicity in a phase I clinical study.
Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10131-6. doi: 10.1073/pnas.0803636105. Epub 2008 Jul 21.
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Production of a monoclonal antibody in plants with a humanized N-glycosylation pattern.
Plant Biotechnol J. 2007 Sep;5(5):657-63. doi: 10.1111/j.1467-7652.2007.00273.x.
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Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide.
J Med Primatol. 2007 Aug;36(4-5):244-53. doi: 10.1111/j.1600-0684.2007.00242.x.
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Sexual and reproductive health: a matter of life and death.
Lancet. 2006 Nov 4;368(9547):1595-607. doi: 10.1016/S0140-6736(06)69478-6.
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Monoclonal antibodies from plants: a new speed record.
Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14645-6. doi: 10.1073/pnas.0607089103. Epub 2006 Sep 25.
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Magnifection--a new platform for expressing recombinant vaccines in plants.
Vaccine. 2005 Mar 18;23(17-18):2042-8. doi: 10.1016/j.vaccine.2005.01.006.

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