Aidietis Audrius, Barysiene Jūrate, Marinskis Germanas, Aidietiene Sigita, Kaireviciūte Diana, Jurkuvenas Paulius, Aganauskiene Jūrate, Bagdonas Kestutis, Jezovas Vladimiras, Laucevicius Aleksandras
Center of Cardiology and Angiology, Clinics of Santariskes, Vilnius University Hospital, Santariskiu 2, Vilnius, Lithuania.
Medicina (Kaunas). 2009;45(3):169-76.
The aim of this study was to evaluate factors influencing the success of atrial fibrillation treatment associated with the sick sinus syndrome after pacemaker implantation.
In 163 patients with sick sinus syndrome followed up after pacemaker implantation, statistical analysis showed that the recurrence of atrial fibrillation increased 2.8 times and 2.5 times when the left atrium or the right atrium, respectively, were increased by 1 cm (P=0.001). In addition, the recurrence of atrial fibrillation increased 2.5 times when the interventricular septum was thickened (P=0.007). Probability of atrial fibrillation recurrence was 2.73 times higher in the presence of grade II mitral regurgitation as compared to absent or grade I mitral regurgitation (P=0.029). The results of atrial fibrillation treatment did not significantly depend on age, gender, duration of atrial fibrillation symptoms, other cardiac structural changes, and concomitant noncardiac diseases.
In patients with sick sinus syndrome, the effectiveness of atrial fibrillation treatment after pacemaker implantation is influenced by enlargement of the left and the right atria, increased interventricular septum thickness, and grade II mitral regurgitation. Evaluation of echocardiographic data before pacemaker implantation has prognostic value for determining the probability of maintenance of sinus rhythm.
本研究旨在评估影响起搏器植入术后与病态窦房结综合征相关的心房颤动治疗成功率的因素。
在163例起搏器植入术后随访的病态窦房结综合征患者中，统计分析显示，当左心房或右心房分别增大1 cm时，心房颤动复发增加2.8倍和2.5倍（P = 0.001）。此外，当室间隔增厚时，心房颤动复发增加2.5倍（P = 0.007）。与无二尖瓣反流或轻度二尖瓣反流相比，中度二尖瓣反流时心房颤动复发概率高2.73倍（P = 0.029）。心房颤动治疗结果并不显著取决于年龄、性别、心房颤动症状持续时间、其他心脏结构改变以及合并的非心脏疾病。
在病态窦房结综合征患者中，起搏器植入术后心房颤动治疗的有效性受左、右心房扩大、室间隔厚度增加以及中度二尖瓣反流的影响。起搏器植入术前超声心动图数据评估对确定窦性心律维持概率具有预后价值。
