Zhou Jiaqiang, Ruan Lingxiang, Li Hong, Wang Qingqing, Zheng Fenping, Wu Fang
Department of Endocrinology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, People's Republic of China.
Endocrine. 2009 Jun;35(3):285-9. doi: 10.1007/s12020-009-9179-x. Epub 2009 Apr 9.
This case study describes a 33-year-old man with Addison's disease who presented with increased plasma adrenocorticotropic hormone (ACTH), normal plasma cortisol, and absent diurnal rhythms. Magnetic resonance imaging (MRI) indicated pituitary hyperplasia. Conventional hydrocortisone replacement therapy may not inhibit high ACTH levels in the morning; however, replacing hydrocortisone with dexamethasone achieved good therapeutic results.
本病例研究描述了一名患有艾迪生病的33岁男性，其血浆促肾上腺皮质激素（ACTH）升高，血浆皮质醇正常，且昼夜节律消失。磁共振成像（MRI）显示垂体增生。常规氢化可的松替代疗法可能无法抑制早晨较高的ACTH水平；然而，用地塞米松替代氢化可的松取得了良好的治疗效果。
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