Gup R S, Sheeler L R, Maeder M C, Tew J M
Neurosurgery. 1982 Dec;11(6):792-4. doi: 10.1227/00006123-198212000-00013.
Primary hypothyroidism may be associated with pituitary enlargement. Two cases of pituitary enlargement with suprasellar extension associated with primary hypothyroidism are presented. In one patient, prompt regression of the pituitary enlargement occurred with replacement doses of L-thyroxine. In the second patient, there was progressive enlargement of the pituitary gland while the patient was on L-thyroxine therapy with documented normalization of serum levels of thyroid-stimulating hormone. We recommend repeat evaluation of all patients with pituitary enlargement that is thought to be secondary to primary hypothyroidism to document regression of pituitary size after L-thyroxine therapy.
原发性甲状腺功能减退可能与垂体增大有关。本文报告了2例与原发性甲状腺功能减退相关的垂体增大并向上延伸至鞍上的病例。其中1例患者，补充左甲状腺素后垂体增大迅速消退。在第2例患者中，患者接受左甲状腺素治疗且血清促甲状腺激素水平已证实正常，但垂体仍进行性增大。我们建议对所有被认为继发于原发性甲状腺功能减退的垂体增大患者进行重复评估，以记录左甲状腺素治疗后垂体大小的消退情况。
