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甲状腺切除术后呼吸并发症的潜在危险因素:一项观察性研究。

Possible risk factors for respiratory complications after thyroidectomy: an observational study.

作者信息

Rahman Ganiyu A

机构信息

Department of Surgery, University of Ilorin Teaching Hospital, Ilorin, Nigeria.

出版信息

Ear Nose Throat J. 2009 Apr;88(4):890-2.

Abstract

It is widely accepted that thyroid surgery is not without morbidity. One well-known postoperative complication is respiratory distress. The aim of this prospective observational study was to determine the incidence of post-thyroidectomy respiratory complications and to identify possible predictive factors. The study population was made up of 262 patients who had undergone thyroidectomy for goiter at the University of Ilorin Teaching Hospital in Nigeria from January 1989 through December 2003. Information was collected on 8 possible predictive factors for respiratory complications: (1) the duration of the goiter, (2) the preoperative status of the recurrent laryngeal nerve, (3) the presence or absence of tracheal narrowing or deviation, (4) the presence or absence of retrosternal extension, (5) the ease or difficulty of endotracheal intubation, (6) the presence or absence of thyroid cancer, (7) the presence or absence of giant goiter, and (8) whether or not the goiter represented a recurrence. Respiratory complications occurred in 20 of the 262 patients (7.6%). Of these 20 patients, 16 (80%) had a goiter of at least 5 years' duration, 12 (60%) had a giant goiter, 5 (25%) had tracheal narrowing, 4 (20%) had a malignant goiter, 3 (15%) had palsy of the recurrent laryngeal nerve preoperatively, and 2 patients each (10%) had retrosternal extension, a difficult intubation, or a recurrent goiter. Twelve patients (60%) had at least 4 of the 8 possible risk factors, and 6 others (30%) had 3 factors. Postoperative tracheotomy was necessary for 4 patients. No deaths occurred. While the findings of this observational study can only suggest the possibility of causation, preoperative factors such as long-standing goiter and giant goiter should be taken into consideration in postoperative management and the prevention of respiratory complications. In addition, the presence of at least 4 of the 8 factors studied should likewise alert the management team.

摘要

人们普遍认为甲状腺手术并非没有并发症。一种众所周知的术后并发症是呼吸窘迫。这项前瞻性观察研究的目的是确定甲状腺切除术后呼吸并发症的发生率,并找出可能的预测因素。研究对象为1989年1月至2003年12月在尼日利亚伊洛林大学教学医院因甲状腺肿接受甲状腺切除术的262例患者。收集了8个可能的呼吸并发症预测因素的信息:(1)甲状腺肿的病程;(2)喉返神经的术前状态;(3)气管狭窄或偏移的有无;(4)胸骨后延伸的有无;(5)气管插管的难易程度;(6)甲状腺癌的有无;(7)巨大甲状腺肿的有无;(8)甲状腺肿是否为复发。262例患者中有20例(7.6%)发生了呼吸并发症。在这20例患者中,16例(80%)甲状腺肿病程至少5年,12例(60%)为巨大甲状腺肿,5例(25%)有气管狭窄,4例(20%)为恶性甲状腺肿,3例(15%)术前有喉返神经麻痹,2例(10%)分别有胸骨后延伸、插管困难或复发性甲状腺肿。12例患者(60%)至少有8个可能危险因素中的4个,另外6例(30%)有3个危险因素。4例患者术后需要气管切开。无死亡病例。虽然这项观察性研究的结果只能提示因果关系的可能性,但在术后管理和预防呼吸并发症时,应考虑如长期存在的甲状腺肿和巨大甲状腺肿等术前因素。此外,所研究的8个因素中至少有4个因素的存在同样应提醒管理团队。

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