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小儿脊髓室管膜瘤的手术考量

Surgical considerations of spinal ependymomas in the pediatric population.

作者信息

Hsu Wesley, Pradilla Gustavo, Constantini Shlomi, Jallo George I

机构信息

Department of Neurosurgery, The Johns Hopkins University School of Medicine, Meyer Bldg. 8-161, 600 N. Wolfe St., Baltimore, MD 21287, USA.

出版信息

Childs Nerv Syst. 2009 Oct;25(10):1253-9. doi: 10.1007/s00381-009-0882-y. Epub 2009 Apr 10.

DOI:10.1007/s00381-009-0882-y
PMID:19360418
Abstract

OBJECTIVES

The objective of this manuscript is to discuss current management strategies regarding pediatric patients with intramedullary spinal cord ependymomas. Spinal ependymoma is the second most common spinal cord tumor in children. The clinical evaluation of these patients, operative techniques, postoperative management considerations, and long-term outcomes are discussed.

INTRODUCTION

The gold standard for the treatment of spinal ependymoma continues to be gross total resection. Patients with residual tumor postoperatively may benefit from adjuvant radiation therapy. Intraoperative monitoring is critical to minimize permanent postoperative neurologic deficit.

CONCLUSION

Patients requiring multilevel laminectomy may benefit from concomitant laminoplasty or instrumented fusion to avoid progressive spinal column deformity.

摘要

目的

本手稿的目的是讨论目前针对小儿脊髓室管膜瘤患者的管理策略。脊髓室管膜瘤是儿童第二常见的脊髓肿瘤。本文讨论了这些患者的临床评估、手术技术、术后管理注意事项及长期预后。

引言

脊髓室管膜瘤治疗的金标准仍然是全切除。术后有残留肿瘤的患者可能从辅助放疗中获益。术中监测对于将术后永久性神经功能缺损降至最低至关重要。

结论

需要进行多级椎板切除术的患者可能受益于同期椎板成形术或器械融合术,以避免脊柱畸形进展。

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本文引用的文献

1
Efficacy of spinal instrumentation and fusion in the prevention of postlaminectomy spinal deformity in children with intramedullary spinal cord tumors.脊柱内固定融合术在预防儿童髓内脊髓肿瘤后路椎板切除术后脊柱畸形中的疗效
J Pediatr Orthop. 2008 Mar;28(2):244-9. doi: 10.1097/BPO.0b013e3181623819.
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Resection of intramedullary spinal cord tumors in children: assessment of long-term motor and sensory deficits.儿童脊髓髓内肿瘤切除术:长期运动和感觉功能障碍评估
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Incidence of spinal deformity after resection of intramedullary spinal cord tumors in children who underwent laminectomy compared with laminoplasty.
术中经颅运动诱发电位和体感诱发电位的变化对脊髓髓内肿瘤患儿预后的预测作用
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Intramedullary medullocervical ependymoma--surgical treatment, functional recovery, and long-term outcome.髓内延髓颈段室管膜瘤——手术治疗、功能恢复及长期预后
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与椎板成形术相比,接受椎板切除术的儿童髓内脊髓肿瘤切除术后脊柱畸形的发生率。
J Neurosurg Pediatr. 2008 Jan;1(1):57-62. doi: 10.3171/PED-08/01/057.
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Risk factors for progressive spinal deformity following resection of intramedullary spinal cord tumors in children: an analysis of 161 consecutive cases.儿童髓内脊髓肿瘤切除术后脊柱畸形进展的危险因素:161例连续病例分析
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Neurological outcome after resection of intramedullary spinal cord tumors in children.儿童髓内脊髓肿瘤切除术后的神经功能转归
Childs Nerv Syst. 2008 Jan;24(1):93-7. doi: 10.1007/s00381-007-0446-y. Epub 2007 Jul 31.
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Long term outcome with post-operative radiation therapy for spinal canal ependymoma.椎管内室管膜瘤术后放疗的长期疗效
J Neurooncol. 2007 May;83(1):85-9. doi: 10.1007/s11060-006-9310-2. Epub 2007 Jan 6.
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Cervical spine deformity associated with resection of spinal cord tumors.与脊髓肿瘤切除相关的颈椎畸形。
Neurosurg Focus. 2006 Feb 15;20(2):E2.
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ORTHOPAEDIC ASPECTS OF INTRASPINAL TUMORS IN INFANTS AND CHILDREN.婴幼儿脊髓内肿瘤的骨科问题
J Bone Joint Surg Am. 1965 Mar;47:223-48.
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Pediatrics. 1959 Jun;23(6):1152-9.
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Spinal sagittal malalignment following surgery for primary intramedullary tumours in children.儿童原发性髓内肿瘤手术后的脊柱矢状面排列不齐。
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