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经阴道注射甲氨蝶呤和氯化钾治疗有活力的剖宫产瘢痕妊娠。

Treatment of a viable caesarean scar pregnancy with transvaginal methotrexate and potassium chloride injection.

出版信息

Arch Gynecol Obstet. 2009 Nov;280(5):869-72. doi: 10.1007/s00404-009-1070-8. Epub 2009 Apr 10.

Abstract

PURPOSE

To present a case of an ectopic pregnancy in a previous caesarean scar in a woman who wishes to preserve her fertility, and its treatment with the local administration of potassium chloride (KCl) and methotrexate (MTX) via a transvaginal needle.

CASE

A 35-year-old woman with a viable caesarean scar pregnancy was referred to our hospital. After an unsuccessful treatment attempt by administering 60 mg systemic methotrexate, the patient was treated with local administration of KCl and MTX using a transvaginal needle. The persistent ectopic mass was removed with dilatation and curettage (D&C) 1 week later. The patient had no complications and the treatment was successful in the follow-up examinations.

CONCLUSION

Local MTX and KCl treatment using a transvaginal needle together with D&C can avoid unnecessary laparotomy, and helps to preserve the fertility of most women with a caesarean scar pregnancy.

摘要

目的

介绍一位希望保留生育能力的妇女在先前剖宫产瘢痕处发生异位妊娠的病例,并采用经阴道针管局部给予氯化钾(KCl)和甲氨蝶呤(MTX)的方法对其进行治疗。

病例

一名 35 岁妇女患有活胎剖宫产瘢痕妊娠,被转诊至我院。在给予 60mg 全身甲氨蝶呤治疗失败后,对患者采用经阴道针管局部给予 KCl 和 MTX 的方法进行治疗。1 周后,通过扩张和刮宫术(D&C)切除了持续存在的异位肿块。患者无并发症,随访检查结果治疗成功。

结论

采用经阴道针管局部给予 MTX 和 KCl 联合 D&C 的方法治疗,可以避免不必要的剖腹手术,有助于保留大多数剖宫产瘢痕妊娠妇女的生育能力。

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