Department of Toxicology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
Int J Food Sci Nutr. 2009 May;60(3):206-9. doi: 10.1080/09637480701690311.
Nitrites are responsible for methemoglobinemia, to which infants younger than 6 months are thought to be the most susceptible population. This study aimed to detect whether there was any nitrite contamination in infant formulas and baby foods marketed in Turkey and to estimate possible toxicological risks in this sensitive physiological period. For this purpose, the samples were randomly collected and divided into four groups: milk-based, cereal-based, vegetable-based, and fruit-based. An easy and reliable spectrophotometric method was used by modifying the Griess method. The average nitrite contamination was found to be 204.07+/-65.80 microg/g in 42 samples, with 1,073 microg/g maximum. According to the results, baby and infant formulas include various nitrite levels; nitrite contamination might come from several sources during manufacturing, and so extreme attention must be given throughout the manufacturing process of food for infants.
亚硝酸盐可导致高铁血红蛋白血症,6 个月以下的婴儿被认为是最易感染人群。本研究旨在检测土耳其市售婴儿配方奶粉和婴儿食品中是否存在亚硝酸盐污染,并评估该敏感生理时期可能存在的毒理学风险。为此,我们随机采集了 42 个样本,分为基于奶、基于谷物、基于蔬菜和基于水果四组,采用改良的格里斯法进行简单、可靠的分光光度法检测。结果显示,42 个样本中亚硝酸盐污染的平均值为 204.07+/-65.80 microg/g,最高值为 1073 microg/g。根据结果,婴儿配方奶粉和婴儿食品中含有不同水平的亚硝酸盐;在生产过程中,亚硝酸盐污染可能来自多个来源,因此在婴儿食品生产过程中必须高度重视。