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在一个无法进行妊娠终止的地区对染色体异常进行产前筛查。

Prenatal screening for chromosome abnormalities in a region with no access to termination of pregnancy.

作者信息

Paolini Cynthia I, Gadow Andrea, Petracchi Florencia, Igarzabal Laura, Quadrelli Roberto, Gadow Enrique C

机构信息

Department of Psychiatry, Center for Medical Education and Clinical Research CEMIC. University Hospital, Buenos Aires, Argentina.

出版信息

Prenat Diagn. 2009 Jul;29(7):659-63. doi: 10.1002/pd.2270.

Abstract

OBJECTIVE

To analyze the different variables that affect couples' decision-making about prenatal screening of chromosome abnormalities in a population with limited access to prenatal diagnosis and no legal termination of pregnancy (TOP).

METHODS

From February through August 2004, 79 couples who requested for prenatal screening at centers from Argentina and Uruguay participated in a study. A cross-sectional survey was administered to assess attitudes toward prenatal screening, the decision-making process, and knowledge and attitudes toward TOP.

RESULTS

Mean maternal age was 32.8 +/- 0.4 years. Among the couples, 88.61% knew that TOP due to fetal anomalies is not legal in their countries. When asked about the possibility of TOP in case of a serious fetal anomaly, 53% would contemplate this option.

CONCLUSION

Prenatal screening is a common practice worldwide. However, unlike most developed countries, our region has a limited access to prenatal diagnosis and no legal TOP. Those couples who stated that 'reassurance about fetal well-being' was the most important reason to perform prenatal screening had more positive attitudes toward TOP than those who considered this screening important 'to be better prepared to receive the baby'. Our findings can be used to inform and revise current health-care policies.

摘要

目的

分析在产前诊断机会有限且无合法终止妊娠(TOP)的人群中,影响夫妻关于染色体异常产前筛查决策的不同变量。

方法

2004年2月至8月,79对在阿根廷和乌拉圭各中心要求进行产前筛查的夫妻参与了一项研究。进行了一项横断面调查,以评估对产前筛查的态度、决策过程以及对TOP的知识和态度。

结果

产妇平均年龄为32.8±0.4岁。在这些夫妻中,88.61%知道因胎儿异常而进行TOP在他们国家是不合法的。当被问及在出现严重胎儿异常时进行TOP的可能性时,53%的人会考虑这个选择。

结论

产前筛查在全球是一种常见做法。然而,与大多数发达国家不同,我们地区产前诊断机会有限且无合法的TOP。那些表示“对胎儿健康状况放心”是进行产前筛查最重要原因的夫妻,对TOP的态度比那些认为这种筛查重要“为更好地迎接宝宝做准备”的夫妻更积极。我们的研究结果可用于为当前的医疗保健政策提供信息并进行修订。

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