在西班牙加泰罗尼亚地区的药店无处方销售抗生素的情况。
The sale of antibiotics without prescription in pharmacies in Catalonia, Spain.
作者信息
Llor Carl, Cots Josep Maria
机构信息
Primary Care Center Jaume I, University Rovira i Virgili, Tarragona, Spain.
出版信息
Clin Infect Dis. 2009 May 15;48(10):1345-9. doi: 10.1086/598183.
BACKGROUND
Current regulations in Spain state that antibiotics cannot be sold without a medical prescription. The objective of this study was to quantify the percentage of pharmacies selling antibiotics without an official medical prescription in Catalonia, Spain, by the simulation of 3 different clinical cases presented by actors.
METHODS
A prospective study was performed from January through May 2008. Three different cases were presented at pharmacies: sore throat, acute bronchitis, and a urinary tract infection. Three levels of demand were used to convince the pharmacists to sell an antibiotic.
RESULTS
A total of 197 pharmacies were visited. Antibiotics were obtained from 55 (79.7%) of 69 pharmacies when a urinary tract infection was simulated, 24 (34.8%) of 69 pharmacies when a sore throat was simulated, and 10 (16.9%) of 59 pharmacies when acute bronchitis was simulated (P < .001). Among the pharmacies that sold antibiotics, the pharmacists provided an explanation as to the number of times per day the drug should be taken in 84.3%, explained the duration of treatment in 68.7%, and inquired about allergies prior to the sale of the antibiotic in only 16.9%. Of the 108 pharmacies that did not sell the antibiotics, only 57 (52.8%) explained that they could not be given over the counter for health care reasons or to avoid antibiotic resistance.
CONCLUSIONS
These results demonstrate that, although illegal, the sale of antibiotics without a prescription continues in Spain. This should be taken into account by countries that are currently considering the possibility of making some antibiotics available over the counter.
背景
西班牙现行法规规定,抗生素未经医生处方不得出售。本研究的目的是通过模拟演员呈现的3种不同临床病例,量化西班牙加泰罗尼亚地区无官方医生处方出售抗生素的药店比例。
方法
于2008年1月至5月进行了一项前瞻性研究。在药店呈现了3种不同病例:咽喉痛、急性支气管炎和尿路感染。使用3种不同程度的诉求来说服药剂师出售抗生素。
结果
共走访了197家药店。模拟尿路感染时,69家药店中有55家(79.7%)出售了抗生素;模拟咽喉痛时,69家药店中有24家(34.8%)出售了抗生素;模拟急性支气管炎时,59家药店中有10家(16.9%)出售了抗生素(P <.001)。在出售抗生素的药店中,药剂师对84.3%的患者说明了药物每日服用次数,对68.7%的患者说明了治疗疗程,而在出售抗生素前询问过敏史的仅占16.9%。在未出售抗生素的108家药店中,只有57家(52.8%)解释称因医疗保健原因或为避免抗生素耐药性不能非处方给药。
结论
这些结果表明,尽管违法,但在西班牙无处方出售抗生素的情况仍在继续。目前正在考虑将某些抗生素非处方销售的国家应考虑到这一点。