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抗菌药物耐药性:过去、现在与未来之路

Antimicrobial resistance: Past, present, and way forward.

作者信息

Rath Ramashankar, Kharya Pradip, Mohanty Aroop, Koparkar Anil R, Dixit Anand M, Joshi Hari Shanker, Hada Vivek

机构信息

Department of Community and Family Medicine, All India Institute of Medical sciences, Gorakhpur, Uttar Pradesh, India.

Department of Microbiology, All India Institute of Medical sciences, Gorakhpur, Uttar Pradesh, India.

出版信息

Indian J Community Med. 2024 Dec;49(Suppl 2):S222-S227. doi: 10.4103/ijcm.ijcm_769_24. Epub 2024 Dec 30.

DOI:10.4103/ijcm.ijcm_769_24
PMID:40124865
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11927809/
Abstract

Antimicrobial resistance (AMR) is one of the important public health problems across the world. Low-middle-income countries are facing the problem more strongly than the high-income countries. AMR is likely to increase the cost of healthcare expenditure over the years. Over the years, various factors like unprecedented use of the antimicrobials in humans, animals, and plants or vegetations and over-the-counter sell of the antibiotics without prescription along with poor sanitation have led to the development and transfer of AMR across the various animal groups. To tackle the issue of the AMR in the country, the Government of India has launched the national program for containment of AMR in 2013 with six identified domains. A containment plan is currently being executed but yet to achieve the full extent as intended. Programmatic consideration aimed to address all the components of AMR development of AMR and its transmission across all levels of health care.

摘要

抗菌药物耐药性(AMR)是全球重要的公共卫生问题之一。中低收入国家比高收入国家面临这一问题的情况更为严峻。多年来,抗菌药物耐药性可能会增加医疗保健支出成本。多年来,诸如在人类、动物、植物或植被中前所未有的抗菌药物使用、无处方非处方药销售抗生素以及卫生条件差等各种因素,导致了抗菌药物耐药性在不同动物群体中的产生和传播。为解决该国的抗菌药物耐药性问题,印度政府于2013年启动了遏制抗菌药物耐药性的国家计划,确定了六个领域。目前正在执行一项遏制计划,但尚未达到预期的全部效果。规划性考虑旨在解决抗菌药物耐药性产生及其在各级医疗保健中传播的所有组成部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706d/11927809/f4d617758262/IJCM-49-222-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706d/11927809/e3cb8ac1aa13/IJCM-49-222-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706d/11927809/93d314bab856/IJCM-49-222-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706d/11927809/f4d617758262/IJCM-49-222-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706d/11927809/e3cb8ac1aa13/IJCM-49-222-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706d/11927809/93d314bab856/IJCM-49-222-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706d/11927809/f4d617758262/IJCM-49-222-g003.jpg

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本文引用的文献

1
Antibiotic-Dispensing Patterns and Awareness of Anti-microbial Resistance Among the Community Pharmacists in South-Central India.印度中南部社区药剂师的抗生素配药模式及对抗菌素耐药性的认知
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Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis.
2019 年全球细菌对抗菌药物耐药性的负担:系统分析。
Lancet. 2022 Feb 12;399(10325):629-655. doi: 10.1016/S0140-6736(21)02724-0. Epub 2022 Jan 19.
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Global antibiotic consumption and usage in humans, 2000-18: a spatial modelling study.全球人类抗生素消费与使用量,2000-2018 年:空间建模研究。
Lancet Planet Health. 2021 Dec;5(12):e893-e904. doi: 10.1016/S2542-5196(21)00280-1. Epub 2021 Nov 12.
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ICMR's Antimicrobial Resistance Surveillance system (-AMRSS): a promising tool for global antimicrobial resistance surveillance.印度医学研究理事会的抗菌药物耐药性监测系统(-AMRSS):全球抗菌药物耐药性监测的一个有前景的工具。
JAC Antimicrob Resist. 2021 Mar 27;3(1):dlab023. doi: 10.1093/jacamr/dlab023. eCollection 2021 Mar.
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Over-the-counter antibiotic sales in community and online pharmacies, China.中国社区和在线药店的非处方抗生素销售。
Bull World Health Organ. 2020 Jul 1;98(7):449-457. doi: 10.2471/BLT.19.242370. Epub 2020 Apr 21.
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Over-the-counter antibiotic dispensing by pharmacies: a standardised patient study in Udupi district, India.印度乌杜皮地区药店非处方抗生素配药情况:一项标准化患者研究
BMJ Glob Health. 2019 Nov 1;4(6):e001869. doi: 10.1136/bmjgh-2019-001869. eCollection 2019.
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An overview of the antimicrobial resistance mechanisms of bacteria.细菌抗菌耐药机制概述。
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Inappropriately prescribed and over-the-counter antimicrobials in the Brazilian Amazon Basin: We need to promote more rational use even in remote places.在巴西亚马逊流域,不适当开具处方和非处方的抗菌药物:即使在偏远地区,我们也需要促进更合理的使用。
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Over-the-counter antibiotics in Saudi Arabia, an urgent call for policy makers.沙特阿拉伯的非处方抗生素,向政策制定者发出的紧急呼吁。
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