Devynck M A, Pernollet M G, Matthews P G, Meyer P
C R Acad Hebd Seances Acad Sci D. 1977 Apr 4;284(14):1293-6.
Distinct and specific binding sites for 3H-angiotensin II (A II) AND 3H-angiotensin III (A III) have been demonstrated in Rat adrenal gland preparations. A III binding sites have the highest affinity (KD29C1-2.10(-10)M) for the 2-8 heptapeptide. This suggests the possibility of a separate and distinct physiological role for the 2-8 heptapeptide, mediated via such A III binding sites.
在大鼠肾上腺制剂中已证实存在3H-血管紧张素II(A II)和3H-血管紧张素III(A III)独特且特异的结合位点。A III结合位点对2-8七肽具有最高亲和力(KD29C1 - 2.10(-10)M)。这表明2-8七肽可能通过此类A III结合位点介导,具有独立且独特的生理作用。