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Aldehyde-fuchsin: a new stain for elastic tissue.醛复红:一种用于弹性组织的新染色剂。
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Extraction of collagen from tissues.从组织中提取胶原蛋白。
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Fibulin-5/DANCE is essential for elastogenesis in vivo.纤连蛋白-5/弹性纤维微原纤维结合蛋白对体内弹性纤维生成至关重要。
Nature. 2002 Jan 10;415(6868):171-5. doi: 10.1038/415171a.
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Quantification of elastin from the mouse lung during postnatal development.出生后发育期间小鼠肺中弹性蛋白的定量分析。
Exp Lung Res. 2001 Oct-Nov;27(7):533-45. doi: 10.1080/019021401753181818.
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Perinatal lethality and endothelial cell abnormalities in several vessel compartments of fibulin-1-deficient mice.纤连蛋白-1缺陷小鼠多个血管腔室中的围产期致死率及内皮细胞异常
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A contribution to the theory of biological staining based on the principles for structural organization of biological macromolecules.基于生物大分子结构组织原理对生物染色理论的一项贡献。
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Lung morphogenesis revisited: old facts, current ideas.重新审视肺形态发生:旧有事实,当前观点。
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Impaired distal airway development in mice lacking elastin.缺乏弹性蛋白的小鼠远端气道发育受损。
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Matrix metalloproteinases and tissue inhibitor of metalloproteinase-2 in fetal rabbit lung.基质金属蛋白酶与金属蛋白酶组织抑制剂-2在胎兔肺中的研究
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Matrix metalloproteinases in renal development and disease.基质金属蛋白酶在肾脏发育和疾病中的作用
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产前发育期间小鼠肺弹性蛋白的定量分析。

Quantification of mouse lung elastin during prenatal development.

作者信息

Rodrigues Paula, Gonçalves Carlos, Honório Ana, Barros José, Bairos Vasco

机构信息

Department of Pathology and Veterinary Clinics - University of Trás-os-Montes e Alto Douro, (UTAD) Vila Real, Portugal; Center for Animal and Veterinary Sciences, UTAD, Vila Real, Portugal.

出版信息

Open Respir Med J. 2008;2:46-51. doi: 10.2174/1874306400802010046. Epub 2008 May 15.

DOI:10.2174/1874306400802010046
PMID:19365535
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2606651/
Abstract

Elastic fibres play a crucial function during the process of lung alveolisation. During the perinatal period, any changes in the elastogenic process during foetal development may result in permanent lifetime defects. In pre-natal life, well-developed pulmonary elastic fibres should favor the pre-natal maturation of the lung and an enhanced alveolisation, which in many species, such as humans begins only after birth. The authors present a quantitative study by image analysis and by high-pressure liquid chromatography (HPLC) of the mouse lungs' elastic fibre content from the 15th till the 19th gestational day.

摘要

弹性纤维在肺泡形成过程中发挥着关键作用。在围产期,胎儿发育过程中弹性生成过程的任何变化都可能导致终身永久性缺陷。在出生前,发育良好的肺弹性纤维应有助于肺的产前成熟和增强肺泡化,而在许多物种中,如人类,肺泡化仅在出生后才开始。作者通过图像分析和高压液相色谱法(HPLC)对妊娠第15天至第19天小鼠肺弹性纤维含量进行了定量研究。