高危妊娠的生化与多普勒超声监测比较

[Comparison of biochemical and Doppler sonographic monitoring of high-risk pregnancies].

作者信息

Steiner H, Schaffer H, Lassmann R, Staudach A, Batka M

机构信息

Landesfrauenklinik Salzburg.

出版信息

Geburtshilfe Frauenheilkd. 1991 Jul;51(7):540-3. doi: 10.1055/s-2007-1026195.

DOI:10.1055/s-2007-1026195

PMID:1936862

Abstract

We performed in 113 patients at least three simultaneous determinations of serum-HPL and oestriol in 24-hour urine samples, as well as Doppler flow studies at the arcuate artery (AA), umbilical artery (UA), foetal aorta and internal carotid, because of suspicion of IUGR. The diagnostic value was studied with regard to IUGR, placental weight and mode of delivery. Concerning the detection of IUGR, the superiority of Doppler parameters (AA, UA) is shown. In the total number of patients, the rates for sensitivity and specificity for UA (78/91%) and AA (58/89%) exceed the hormone parameters. Oestriol, in particular, (13/63%) shows a marked difference, but even HPL (37/63%) cannot compete with respect to diagnostic value.

摘要

由于怀疑胎儿宫内生长受限（IUGR），我们对113例患者进行了检测，至少三次同时测定24小时尿样中的血清人胎盘催乳素（HPL）和雌三醇，以及弓形动脉（AA）、脐动脉（UA）、胎儿主动脉和颈内动脉的多普勒血流研究。研究了这些指标对于IUGR、胎盘重量和分娩方式的诊断价值。关于IUGR的检测，显示出多普勒参数（AA、UA）的优越性。在患者总数中，UA（78/91%）和AA（58/89%）的敏感性和特异性高于激素参数。尤其是雌三醇（13/63%）显示出明显差异，但即使是HPL（37/63%）在诊断价值方面也无法与之竞争。