来自轮叶香科的枞酸型二萜类化合物。

Abietane diterpeniods from Hyptis verticillata.

作者信息

Porter Roy B R, Biggs Duanne A C, Reynolds William F

机构信息

Department of Chemistry, University of the West Indies, Mona, Kingston 7, Jamaica.

出版信息

Nat Prod Commun. 2009 Jan;4(1):15-8.

PMID:19370867

Abstract

Seven abietane diterpenoids were isolated from the roots of Hyptis verticillata (Labiatae). One is a novel natural product, 7-acetoxy-16-benzoxy-12-hydroxyabieta-8,12-diene-11,14-dione (1), while the other six known compounds are 11,14 dihydroxy-12-methoxyabieta-8,11,13-triene-7-one (2), 11,14-dihydroxy-12-methoxy- 18(4-->3betaH) abeo-abieta-4(19),8,11,13-tetraene-7-one (3), 7-acetoxy-12-methoxyabieta-8,12-diene-11,14-dione (4), royleanone (5), 7,6-dehydroroyleanone (6) and 7-acetoxyhorminone (7). All structures were elucidated by spectroscopic and mass spectrometric means.

摘要

从轮叶香科（唇形科）植物的根中分离出七种松香烷二萜类化合物。其中一种是新型天然产物，7-乙酰氧基-16-苄氧基-12-羟基枞-8,12-二烯-11,14-二酮（1），另外六种已知化合物分别为11,14-二羟基-12-甲氧基枞-8,11,13-三烯-7-酮（2）、11,14-二羟基-12-甲氧基-18(4→3βH)去甲枞-4(19),8,11,13-四烯-7-酮（3）、7-乙酰氧基-12-甲氧基枞-8,12-二烯-11,14-二酮（4）、罗伊酮（5）、7,6-脱氢罗伊酮（6）和7-乙酰氧基霍米酮（7）。所有结构均通过光谱和质谱手段进行了阐明。