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穗花香薷中的松香烷二萜。

Abietane diterpenes from Hyptis suaveolens.

机构信息

Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand.

出版信息

Chem Biodivers. 2013 Aug;10(8):1494-500. doi: 10.1002/cbdv.201200213.

Abstract

Investigation of the constituents of the whole plant of Hyptis suaveolens led to the isolation of three new abietane diterpenes, isosuaveolic acid (1), 8α,9α-epoxysuaveolic acid (2), and 14-O-methylsuaveolic acid (3), together with eleven known compounds. The structures of 1-3 were established by spectroscopic methods and chemical correlations. Some isolates were tested for their antimycobacterial and cytotoxic activities.

摘要

对紫背天葵全草的化学成分研究导致了三个新的枞酸二萜的分离,即异土木香酸(1)、8α,9α-环氧土木香酸(2)和 14-O-甲基土木香酸(3),以及十一种已知化合物。通过光谱方法和化学相关确定了 1-3 的结构。一些分离物进行了抗分枝杆菌和细胞毒性活性测试。

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