Sriskandan Neshe, Moody Andrew, Howlett David C
Department of Radiology, Eastbourne District General Hospital, Eastbourne, East Sussex, UK.
Br J Oral Maxillofac Surg. 2010 Jan;48(1):58-60. doi: 10.1016/j.bjoms.2009.03.005. Epub 2009 Apr 15.
Hypersalivation associated with cerebral palsy may be treated with injection of botulinum toxin A (BTX-A) into the submandibular gland, and the use of ultrasound permits its accurate administration. In our series four patients with cerebral palsy and hypersalivation had bilateral ultrasound-guided injection of BTX-A into the submandibular gland. At 4 weeks there was objective improvement in all patients and subjective improvement in three. The only reported side effect was the temporary inability to retain prosthetic orbital globes in one patient. Ultrasound-guided injection of BTX-A for hypersalivation is effective, and side effects are rare, but they have yet to be fully described.
与脑瘫相关的流涎过多可用向颌下腺注射A型肉毒杆菌毒素（BTX-A）来治疗，而超声的应用可使其准确给药。在我们的病例系列中，4例患有脑瘫和流涎过多的患者接受了在超声引导下向双侧颌下腺注射BTX-A的治疗。4周时，所有患者均有客观改善，3例有主观改善。唯一报告的副作用是1例患者暂时无法固定义眼。超声引导下注射BTX-A治疗流涎过多有效，且副作用罕见，但尚未得到充分描述。
