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雄激素受体作用机制。

Mechanism of androgen receptor action.

作者信息

Li Jin, Al-Azzawi Farook

机构信息

Gynaecology Research Unit, University Hospitals of Leicester, Victoria Building, Leicester Royal Infirmary, Leicester LE1 5WW, United Kingdom.

出版信息

Maturitas. 2009 Jun 20;63(2):142-8. doi: 10.1016/j.maturitas.2009.03.008. Epub 2009 Apr 15.

Abstract

Recent research provides a much more detailed understanding of the role of the androgen receptor in normal human development and physiology, its structure, and its functioning. This review discusses genomic and non-genomic actions of the androgen receptor, as well as their co-regulators. We also explore several clinically relevant aspects of the molecular biology of the androgen receptor and its co-regulators.

摘要

最近的研究对雄激素受体在正常人类发育和生理学中的作用、其结构及功能有了更为详细的了解。本综述讨论了雄激素受体的基因组和非基因组作用及其共调节因子。我们还探讨了雄激素受体及其共调节因子分子生物学的几个临床相关方面。

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