高压氧治疗一氧化碳中毒期间的癫痫发作：病例系列及五年经验
Seizure during hyperbaric oxygen therapy for carbon monoxide toxicity: a case series and five-year experience.
作者信息
Sanders Robert W, Katz Kenneth D, Suyama Joe, Akhtar Jawaid, O'Toole Kevin S, Corll Diann, Ladenburger Regan N
机构信息
Department of Emergency Medicine, University of Pittsburgh Medical Center, Presbyterian Hospital, Pittsburgh, PA, USA.
出版信息
J Emerg Med. 2012 Apr;42(4):e69-72. doi: 10.1016/j.jemermed.2008.12.017. Epub 2009 Apr 15.
BACKGROUND
Hyperbaric oxygen (HBO) therapy is recommended to reduce the delayed neurologic sequelae resulting from carbon monoxide (CO) toxicity. Although HBO is generally well tolerated, there exists a risk of seizure in all patients that may be increased in patients with predisposing factors including: fever, hypothermia, prior seizure, or brain injury.
CASE REPORT
We present two cases of patients without known risk factors who experienced seizures associated with HBO therapy during treatment for CO toxicity.
CONCLUSION
This facility's 5-year experience and a review of the germane literature are also presented to elucidate the risk factors and incidence of seizures in patients treated with HBO for CO toxicity.
背景
推荐采用高压氧（HBO）疗法来减轻一氧化碳（CO）中毒所致的迟发性神经后遗症。尽管HBO疗法通常耐受性良好，但所有患者都存在癫痫发作的风险，而具有以下易感因素的患者风险可能会增加：发热、体温过低、既往癫痫发作或脑损伤。
病例报告
我们报告两例在CO中毒治疗期间接受HBO治疗时出现与HBO疗法相关癫痫发作的患者，这两名患者并无已知的风险因素。
结论
本文还介绍了该机构5年的经验以及对相关文献的回顾，以阐明接受HBO治疗CO中毒患者的癫痫发作风险因素和发生率。
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