Niv Y, Hadari A, Asaf V, Oren M
Gastroenterology Unit, Rebecca Sieff Government Hospital, Safed.
Harefuah. 1991 Jun 2;120(11):647-8.
Postoperative gastrointestinal fistula formation is not rare, and is accompanied by considerable morbidity and mortality. Somatostatin, a potential, universal endocrine and exocrine inhibitor, is a peptide synthesized in the nervous system and the gastrointestinal tract. We describe 2 men, 58 and 53 years old, respectively, with postoperative fistulas, the first after pancreatic-jejunal and the second after jejunal anastomosis. 7 and 3 days, respectively, after starting a synthetic somatostatin analogue (SMS 201-995), discharge from the fistulas decreased and they closed completely.
术后胃肠瘘的形成并不罕见，且伴有相当高的发病率和死亡率。生长抑素是一种潜在的、通用的内分泌和外分泌抑制剂，是在神经系统和胃肠道中合成的一种肽。我们描述了两名男性，分别为58岁和53岁，他们均有术后瘘，第一例是胰空肠吻合术后，第二例是空肠吻合术后。在开始使用合成生长抑素类似物（SMS 201-995）后，分别于7天和3天，瘘管排出物减少并完全闭合。
