Coutinho Jonathan M, Majoie Charles B L M, Coert Bert A, Stam Jan
Stroke. 2009 Jun;40(6):2233-5. doi: 10.1161/STROKEAHA.108.543421. Epub 2009 Apr 16.
Thirteen percent of patients with cerebral venous and sinus thrombosis (CVST) has a poor clinical outcome. In patients with a poor prognosis, endovascular thrombolysis can be considered, but this procedure does not appear to be beneficial in patients with impending transtentorial herniation because of large hemorrhagic venous infarcts. Therefore, halfway through 2006, we changed our policy to decompressive hemicraniectomy in these patients.
Patients with CVST and impending herniation attributable to venous infarcts were eligible for surgical intervention. Since 2006 we consecutively treated 3 patients with decompressive hemicraniectomy. Two patients had an excellent outcome. The third patient, who had been comatose for at least 12 hours before surgery, died despite intervention.
Our data suggest that decompressive hemicraniectomy can be life-saving and can result in an excellent outcome in patients with severe CVST.
13%的脑静脉窦血栓形成(CVST)患者临床预后较差。对于预后不良的患者,可考虑血管内溶栓治疗,但由于大面积出血性静脉梗死导致即将发生小脑幕切迹疝的患者,该治疗方法似乎并无益处。因此,在2006年年中,我们对这些患者的治疗策略改为去骨瓣减压术。
因静脉梗死导致即将发生脑疝的CVST患者符合手术干预条件。自2006年以来,我们连续对3例患者实施了去骨瓣减压术。2例患者预后良好。第3例患者在手术前已昏迷至少12小时,尽管进行了干预仍死亡。
我们的数据表明,去骨瓣减压术可挽救生命,对于重症CVST患者可带来良好的预后。