Brown Richard A, Lejuez C W, Strong David R, Kahler Christopher W, Zvolensky Michael J, Carpenter Linda L, Niaura Raymond, Price Lawrence H
Warren Alpert Medical School of Brown University, Butler Hospital, 345 Blackstone Boulevard, Providence, RI 02906, USA.
Nicotine Tob Res. 2009 May;11(5):493-502. doi: 10.1093/ntr/ntp041. Epub 2009 Apr 16.
A significant percentage of smokers attempting cessation lapse to smoking within a matter of days, and current models of relapse devote insufficient attention to such early smoking lapse. Studies attempting to relate severity of nicotine withdrawal symptoms to short-term smoking cessation outcomes have yielded equivocal results. How one reacts to the discomfort of nicotine withdrawal and quitting smoking (i.e., distress tolerance) may be a more promising avenue of investigation with important treatment implications.
The present investigation examined distress tolerance and early smoking lapse using a prospective design. Participants were 81 adult daily smokers recruited through newspaper advertisements targeted at smokers planning to quit smoking without assistance (i.e., no pharmacotherapy or psychosocial treatment; 42 males and 39 females; mean age = 42.6 years, SD = 12.20).
As hypothesized, both greater breath-holding duration and carbon dioxide-enriched air persistence were associated with a significantly lower risk of smoking lapse following an unaided quit attempt. These effects were above and beyond the risk associated with levels of nicotine dependence, education, and history of major depressive disorder, suggesting that distress tolerance and task persistence may operate independently of risk factors such as nicotine dependence and depressive history. In contrast to expectation, persistence on the Paced Auditory Serial Addition Test (a psychological challenge task) was not a significant predictor of earlier smoking lapse.
These results are discussed in relation to refining theoretical models of the role of distress tolerance in early smoking lapse and the utility of such models in the development of specialized treatment approaches for smoking cessation.
相当大比例试图戒烟的吸烟者会在几天内复吸,而目前的复吸模型对这种早期吸烟复吸关注不足。试图将尼古丁戒断症状的严重程度与短期戒烟结果联系起来的研究结果并不明确。一个人如何应对尼古丁戒断和戒烟带来的不适(即痛苦耐受性)可能是一个更有前景的研究途径,对治疗具有重要意义。
本研究采用前瞻性设计,考察痛苦耐受性和早期吸烟复吸情况。参与者是通过报纸广告招募的81名成年每日吸烟者,这些广告针对计划在无辅助情况下戒烟的吸烟者(即不使用药物治疗或心理社会治疗;42名男性和39名女性;平均年龄 = 42.6岁,标准差 = 12.20)。
正如假设的那样,屏气持续时间延长和在富含二氧化碳的空气中的耐受时间延长都与自主戒烟尝试后吸烟复吸风险显著降低相关。这些影响超出了与尼古丁依赖程度、教育程度和重度抑郁症病史相关的风险,这表明痛苦耐受性和任务坚持性可能独立于尼古丁依赖和抑郁病史等风险因素起作用。与预期相反,在听觉连续加法测试(一项心理挑战任务)中的坚持性并不是早期吸烟复吸的显著预测因素。
将这些结果与完善痛苦耐受性在早期吸烟复吸中作用的理论模型以及此类模型在开发专门戒烟治疗方法中的效用进行了讨论。