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视网膜分支静脉阻塞:分类与治疗

Branch retinal vein occlusion: classification and treatment.

作者信息

Parodi Maurizio Battaglia, Bandello Francesco

机构信息

Department of Ophthalmology, University of Udine, Udine, Italy.

出版信息

Ophthalmologica. 2009;223(5):298-305. doi: 10.1159/000213640. Epub 2009 Apr 16.

Abstract

Branch retinal vein occlusion (BRVO) refers to a heterogeneous group of disorders with different clinical aspects, courses, and probably therapy. Depending on the site of the arteriovenous crossing, we can roughly divide BRVO into 3 main groups: major BRVO, hemispheric retinal vein occlusion, and macular BRVO. Main treatment options include laser treatment, corticosteroid administration, anti-VEGF drugs, and sheathotomy with or without vitrectomy. Laser photocoagulation, as demonstrated by the Branch Vein Occlusion Study, represents the gold standard for the treatment of macular edema and ocular neovascularization following BRVO. The limited functional outcomes achievable by means of laser treatment have prompted researchers to try alternative options, with varying results. The recent introduction of combined therapies for macular edema may provide a superior approach in an attempt to improve and stabilize visual acuity over a long-term follow-up.

摘要

视网膜分支静脉阻塞(BRVO)是一组具有不同临床特征、病程且可能需要不同治疗方法的异质性疾病。根据动静脉交叉的部位,我们大致可将BRVO分为3个主要类型:主要BRVO、半球形视网膜静脉阻塞和黄斑BRVO。主要治疗选择包括激光治疗、皮质类固醇给药、抗VEGF药物以及有或无玻璃体切除术的鞘膜切开术。如分支静脉阻塞研究所示,激光光凝是治疗BRVO后黄斑水肿和眼部新生血管的金标准。激光治疗所能达到的有限功能结果促使研究人员尝试其他替代方法,结果各异。近期引入的黄斑水肿联合疗法可能为在长期随访中提高和稳定视力提供一种更好的方法。

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