Simon C
Abt. Allgemeine Pädiatrie der Kinderklinik Kiel.
Fortschr Med. 1991 Jul 30;109(22):447-8.
Since 1980, numerous reports have been published throughout the world on the pathogenic role of Branhamella catarrhalis. Apparently, Branhamella infections have been increasing in many places. Although they can affect various organs, they are most commonly observed in the airways and eye (both in children and adults). Not infrequently, Branhamella catarrhalis causes sepsis, in particular in immunosuppressed patients. The rapid increase in beta-lactamase-forming Branhamella strains results in frequent ineffectiveness of treatment with penicillin. In patients treated with penicillin for a primary infection by other bacteria, a secondary infection due to penicillin-resistant Branhamella organisms can subsequently occur. For treatment, therefore, beta-lactamase-stable antibiotics should be preferred.
自1980年以来，世界各地发表了许多关于卡他布兰汉菌致病作用的报告。显然，卡他布兰汉菌感染在许多地方都呈上升趋势。虽然它们可累及多个器官，但最常见于气道和眼部（儿童和成人均如此）。卡他布兰汉菌常引起败血症，尤其是在免疫抑制患者中。产β-内酰胺酶的卡他布兰汉菌菌株迅速增加，导致青霉素治疗常常无效。在用青霉素治疗其他细菌引起的原发性感染的患者中，随后可能会发生由耐青霉素的卡他布兰汉菌引起的继发性感染。因此，在治疗时应首选对β-内酰胺酶稳定的抗生素。
