马来酸哌克昔林诱发的肝炎。
Perhexiline maleate-induced hepatitis.
作者信息
Satz N, Täuber M, Streuli R, Spycher M A, Maurer R
机构信息
Department of Medicine, University Hospital, Zurich.
出版信息
Hepatogastroenterology. 1991 Aug;38(4):314-6.
PMID:1937378
Abstract
We report on a case of perhexiline maleate-induced hepatitis secondary to a long-term administration of recommended daily dosages of 300 mg. The patient had a spectacular weight loss of 29 kg. He developed hepatitis, which subsided after drug withdrawal. Our electron-microscopic findings with the typical inclusion bodies and impaired hydroxylation capacity point to an underlying metabolic disorder as the pathogenetic mechanism.
摘要
我们报告一例因长期服用推荐日剂量300毫克马来酸哌克昔林而导致的肝炎病例。该患者体重显著减轻29千克。他患上了肝炎，停药后病情缓解。我们的电子显微镜检查结果显示有典型的包涵体以及羟化能力受损，这表明潜在的代谢紊乱是发病机制。
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Perhexiline maleate-induced hepatitis.马来酸哌克昔林诱发的肝炎。
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