Rüchel R
Abteilung Medizinische Mikrobiologie, Universität Göttingen.
Immun Infekt. 1991 Aug;19(4):108-11.
Candida albicans has an advantage on other fungal opportunists, being the only fungus among the normal microbial flora on human mucosa. The potential factors of virulence of C.albicans are essentially responsible for the persistence of the yeast on mucosal surfaces. If the normal regeneration of epithelia is impeded. C.albicans may invade the mucosa. It may penetrate deeply into the host during granulocytopenia or cellular immunodeficiency, apparently using mechanisms of mimicry and the activity of secretory hydrolases.
白色念珠菌相较于其他机会性真菌具有优势，它是人类黏膜正常微生物群中唯一的真菌。白色念珠菌的潜在毒力因素本质上决定了该酵母菌在黏膜表面的持续存在。如果上皮细胞的正常再生受到阻碍，白色念珠菌可能会侵入黏膜。在粒细胞减少或细胞免疫缺陷期间，它可能会深入侵入宿主，显然是利用了模拟机制和分泌水解酶的活性。
