Gow Sheryl P, Waldner Cheryl L
Public Health Agency of Canada, Laboratory of Foodborne Zoonoses, Dept. of Large Animal Clinical Sciences, Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4, Canada.
Prev Vet Med. 2009 Jul 1;90(1-2):55-65. doi: 10.1016/j.prevetmed.2009.03.010. Epub 2009 Apr 19.
Investigators examined antimicrobial drug use practices and reason for treatment as part of a large on-farm observational study of cow-calf herds from western Canada. Reason for treatment and antimicrobial drug use (AMU) were described using data collected during the calving season (January 1 to June 30, 2002). The study included 28,573 calves and 36,634 cows and heifers from 203 beef herds. All herds had more than 50 cows. Individual animal treatment records and a herd-level standardized questionnaire were collected from every herd. During the period of January 1 to June 30, 2002 at least one treatment was reported in 14% (95% CI, 11-17) of calves and 2.7% (95% CI, 2.2-3.4) of cows and heifers from these herds. The median percent of calves reported as treated per farm was 6.5% (range 0-100%) while the median percent of cows and heifers reported as treated was 0.9% (range 0-15%). Antimicrobial drugs used during the calving season were primarily for disease treatment rather than prevention or growth promotion. Diarrhea was the primary reason for treating calves and metritis was the primary reason for treating cows. Parenteral antimicrobial drugs were the most common formulation used in both calves and cows. The most commonly used antimicrobial drugs in these herds were tetracyclines, sulphonamides, and florfenicol. This study provides baseline estimates of the frequency of antimicrobial drug exposure, the types of drugs used, and diseases treated in these cow-calf herds. The challenges identified in collecting these data can be used to improve the design of future on-farm studies.
作为对加拿大西部奶牛-犊牛群进行的一项大型农场观察性研究的一部分,研究人员调查了抗菌药物的使用情况及治疗原因。利用在产犊季节(2002年1月1日至6月30日)收集的数据描述了治疗原因和抗菌药物使用情况。该研究包括来自203个肉牛群的28573头犊牛以及36634头母牛和小母牛。所有牛群的母牛数量均超过50头。从每个牛群收集了个体动物治疗记录和一份牛群水平的标准化问卷。在2002年1月1日至6月30日期间,这些牛群中14%(95%CI,11%-17%)的犊牛以及2.7%(95%CI,2.2%-3.4%)的母牛和小母牛报告至少接受过一次治疗。每个农场报告接受治疗的犊牛的中位数百分比为6.5%(范围0-100%),而报告接受治疗的母牛和小母牛的中位数百分比为0.9%(范围0-15%)。产犊季节使用的抗菌药物主要用于疾病治疗,而非预防或促进生长。腹泻是治疗犊牛的主要原因,子宫内膜炎是治疗母牛的主要原因。注射用抗菌药物是犊牛和母牛中最常用的剂型。这些牛群中最常用的抗菌药物是四环素、磺胺类药物和氟苯尼考。本研究提供了这些奶牛-犊牛群中抗菌药物暴露频率、所用药物类型以及所治疗疾病的基线估计值。收集这些数据过程中发现的挑战可用于改进未来农场研究的设计。