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用于SPES硼中子俘获治疗设施的角度和能量微分中子能谱法。

Angle and energy differential neutron spectrometry for the SPES BNCT facility.

作者信息

d'Errico F, Ciolini R, Di Fulvio A, Reginatto M, Esposito J, Ceballos Sánchez C, Colautti P

机构信息

Department of Mechanical, Nuclear and Production Engineering, University of Pisa, Italy.

出版信息

Appl Radiat Isot. 2009 Jul;67(7-8 Suppl):S141-4. doi: 10.1016/j.apradiso.2009.03.035. Epub 2009 Mar 27.

Abstract

An accelerator-driven thermal neutron facility for boron neutron capture therapy of skin melanoma is currently under construction at the Legnaro National Laboratories, Italy. The installation relies on the production of neutrons from a thick beryllium target bombarded with 5 MeV protons. A complete set of double differential data, i.e. angle- and energy-differential neutron spectra produced by the beryllium target, is necessary for the Monte Carlo-based design of the installation. For this purpose, double differential fluence measurements are currently performed with the "BINS" neutron spectrometer using 5 MeV protons at the "CN" Van de Graaf accelerator. This spectrometer uses a superheated emulsion of dichlorotetrafluoroethane which is sequentially operated at 25, 30, 35, 40, 45, 50 and 55 degrees C and thus provides a series of seven sharp thresholds covering the 0.1-10 MeV neutron energy interval. Deconvolution of the data is performed with the code "MAXED", which is based on the maximum entropy principle. The analysis of our first neutron spectrometry measurements at angles of 0 degrees, 40 degrees, 80 degrees and 120 degrees supports the viability of the BINS spectrometry method for the generation of the required double differential data.

摘要

意大利莱尼亚罗国家实验室正在建造一座用于皮肤黑色素瘤硼中子俘获治疗的加速器驱动热中子设施。该装置依靠用5兆电子伏质子轰击厚铍靶产生中子。对于基于蒙特卡罗方法的装置设计而言,需要一套完整的双微分数据,即铍靶产生的角度和能量微分中子能谱。为此,目前正在“CN”范德格拉夫加速器上使用5兆电子伏质子,通过“BINS”中子谱仪进行双微分注量测量。该谱仪使用二氯四氟乙烷过热乳剂,其依次在25、30、35、40、45、50和55摄氏度下运行,从而提供一系列七个覆盖0.1 - 10兆电子伏中子能量区间的尖锐阈值。数据反卷积使用基于最大熵原理的“MAXED”代码进行。我们在0度、40度、80度和120度角度下的首次中子能谱测量分析支持了BINS能谱法用于生成所需双微分数据的可行性。

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