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用于意大利国家核物理研究所莱尼亚罗国家实验室基于加速器的硼中子俘获治疗设施治疗浅表皮肤黑色素瘤的体表面积建模。

The BSA modeling for the accelerator-based BNCT facility at INFN LNL for treating shallow skin melanoma.

作者信息

Ceballos C, Esposito J

机构信息

INFN Laboratori Nazionali di Legnaro, Via dell'Università, 2, I-35020 Legnaro (PD), Italy.

出版信息

Appl Radiat Isot. 2009 Jul;67(7-8 Suppl):S274-7. doi: 10.1016/j.apradiso.2009.03.074. Epub 2009 Mar 27.

Abstract

The SPES-BNCT ongoing project of the Istituto Nazionale di Fisica Nucleare (INFN) is aimed at the construction at the Laboratori Nazionali di Legnaro (LNL) of an accelerator-based (AB), high-flux thermal neutron beam facility devoted to boron neutron capture therapy (BNCT) experimental treatment of extended skin melanoma, in the framework of SPES (selective production of exotic species) project. The neutron source will be produced via the (9)Be(p,xn) reactions by a 5 MeV, 30 mA proton beam into a thick beryllium target. The resulting neutron spectrum is slowed down using a beam shaping assembly (BSA), for which modeling is in an advanced neutronic design stage. An overview on the BSA current status, based on the Be neutron converter prototype designed and already constructed, is reported.

摘要

意大利国家核物理研究所(INFN)正在进行的SPES-BNCT项目旨在利用SPES(奇特核素的选择性产生)项目框架,在莱尼亚罗国家实验室(LNL)建造一个基于加速器(AB)的高通量热中子束设施,用于扩展型皮肤黑色素瘤的硼中子俘获疗法(BNCT)实验治疗。中子源将通过5 MeV、30 mA的质子束与厚铍靶发生(9)Be(p,xn)反应产生。使用束流整形组件(BSA)使产生的中子能谱慢化,其建模正处于先进的中子学设计阶段。本文报道了基于已设计并建造的铍中子转换器原型的束流整形组件的当前状态概述。

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