针刺治疗癌症患者放射性口干症的一项初步研究。

Acupuncture for radiation-induced xerostomia in patients with cancer: a pilot study.

作者信息

Garcia M Kay, Chiang Joseph S, Cohen Lorenzo, Liu Meide, Palmer J Lynn, Rosenthal David I, Wei Qi, Tung Samuel, Wang Congjun, Rahlfs Thomas, Chambers Mark S

机构信息

Integrative Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

出版信息

Head Neck. 2009 Oct;31(10):1360-8. doi: 10.1002/hed.21110.

DOI:10.1002/hed.21110

PMID:19378325

Abstract

BACKGROUND

This pilot study evaluated if acupuncture can alleviate radiation-induced xerostomia among patients with cancer. Secondary objectives were to assess the effects of acupuncture on salivary flow and quality of life (QOL).

METHODS

Nineteen patients received acupuncture twice a week for 4 weeks.

RESULTS

Xerostomia inventory (XI) and patient benefit questionnaire (PBQ) scores were significantly better after acupuncture on weeks 4 and 8 than at baseline (XI: p = .0004 and .0001; PBQ: p = .0004 and .0011, respectively). For QOL at weeks 4 and 8, there was a significant difference for questions related to head/neck cancer (p = .04 and .006, respectively). At week 8, there was a significant difference in physical well-being (p = .04). At weeks 5 and 8, there were significant differences in the total score (p = .04 and .03, respectively).

CONCLUSIONS

Acupuncture was effective for radiation-induced xerostomia in this small pilot study. Further research is needed.

摘要

背景

本初步研究评估了针灸是否能缓解癌症患者的放射性口干。次要目标是评估针灸对唾液流量和生活质量（QOL）的影响。

方法

19名患者每周接受两次针灸治疗，共4周。

结果

在第4周和第8周针灸治疗后，口干量表（XI）和患者受益问卷（PBQ）得分显著优于基线水平（XI：p = 0.0004和0.0001；PBQ：分别为p = 0.0004和0.0011）。对于第4周和第8周的生活质量，与头颈癌相关的问题存在显著差异（分别为p = 0.04和0.006）。在第8周，身体健康方面存在显著差异（p = 0.04）。在第5周和第8周，总分存在显著差异（分别为p = 0.04和0.03）。