Gauld Leanne Maree
Respiratory Medicine, Royal Children's Hospital, Herston, QLD, Australia.
Dev Med Child Neurol. 2009 May;51(5):350-5. doi: 10.1111/j.1469-8749.2008.03260.x.
Impaired airway clearance leads to recurrent chest infections and respiratory deterioration in neuromuscular weakness. It is frequently the cause of death. Cough is the major mechanism of airway clearance. Cough has several components, and assessment tools are available to measure the different components of cough. These include measuring peak cough flow, respiratory muscle strength, and inspiratory capacity. Each is useful in assessing the ability to generate an effective cough, and can be used to guide when techniques of assisting airway clearance may be effective for the individual and which are most effective. Techniques to assist airway clearance include augmenting inspiration by air stacking, augmenting expiration by assisting the cough, and augmenting both inspiration and expiration with the mechanical insufflator-exsufflator or by direct suctioning via a tracheostomy. Physiotherapists are invaluable in assisting airway clearance, and in teaching patients and their families how to use these techniques. Use of the mechanical insufflator-exsufflator has gained popularity in recent times, but several simpler, more economical methods are available to assist airway clearance that can be used effectively alone or in combination. This review examines the literature available on the assessment and management of impaired airway clearance in neuromuscular weakness.
气道廓清功能受损会导致神经肌肉无力患者反复出现胸部感染和呼吸功能恶化。这常常是死亡的原因。咳嗽是气道廓清的主要机制。咳嗽有几个组成部分,并且有评估工具可用于测量咳嗽的不同组成部分。这些包括测量咳嗽峰值流速、呼吸肌力量和吸气容量。每一项都有助于评估产生有效咳嗽的能力,并且可用于指导何时辅助气道廓清技术对个体可能有效以及哪些技术最有效。辅助气道廓清的技术包括通过叠加吸气增加吸气、通过辅助咳嗽增加呼气,以及使用机械通气-呼气器或通过气管造口直接吸引来增加吸气和呼气。物理治疗师在协助气道廓清以及教导患者及其家属如何使用这些技术方面非常重要。近年来,机械通气-呼气器的使用越来越普遍,但有几种更简单、更经济的方法可用于辅助气道廓清,这些方法可以单独或联合有效使用。本综述研究了关于神经肌肉无力患者气道廓清功能受损的评估和管理的现有文献。