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化学敏感性中的注意偏向与致敏作用。

Attention bias and sensitization in chemical sensitivity.

作者信息

Andersson Linus, Bende Mats, Millqvist Eva, Nordin Steven

机构信息

Department of Psychology, Umeå University, Umeå, Sweden.

出版信息

J Psychosom Res. 2009 May;66(5):407-16. doi: 10.1016/j.jpsychores.2008.11.005. Epub 2009 Jan 20.

Abstract

OBJECTIVE

We investigated whether persons with self-reported chemical sensitivity (CS) have an attention bias and enhanced sensitization to chemical exposure.

METHODS

Chemosomatosensory, olfactory, and auditory event-related potentials (ERPs) were recorded from 21 CS subjects and 17 controls in attend and ignore conditions. Reaction times (RTs) and magnitude estimations of perceived intensity were collected in the attend condition. ERPs were averaged over attention conditions and during the first/second part of the testing.

RESULTS

ERP patterns indicated that CS subjects did not habituate to the same extent as the controls and had difficulties ignoring the chemical exposure. CS subjects had faster overall RT, and the perceived intensities for the chemosomatosensory stimuli did not decrease with time in the CS group, which was the case for the controls.

CONCLUSIONS

These results indicating attention bias and enhanced sensitization in CS suggest alterations in central, cognitive responses to chemical exposure.

摘要

目的

我们研究了自我报告有化学物质敏感(CS)的人是否存在注意力偏差以及对化学暴露的致敏增强情况。

方法

在注意力集中和忽略两种条件下,记录了21名CS受试者和17名对照者的化学体感、嗅觉和听觉事件相关电位(ERP)。在注意力集中条件下收集反应时间(RT)和感知强度的量级估计值。ERP在注意力条件以及测试的第一/第二部分期间进行平均。

结果

ERP模式表明,CS受试者与对照组的习惯化程度不同,且难以忽略化学暴露。CS受试者的总体RT更快,并且化学体感刺激的感知强度在CS组中并未随时间下降,而对照组则是这样。

结论

这些表明CS存在注意力偏差和致敏增强的结果提示,对化学暴露的中枢认知反应发生了改变。

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