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A study relating to bioavailability and renal elimination of bismuth after oral administration of basic bismuth nitrate.

作者信息

Behrendt W A, Gröger C, Kuhn D, Schulz H U, Topfmeier P

机构信息

Temmler Pharma GmbH, Marburg, Germany.

出版信息

Int J Clin Pharmacol Ther Toxicol. 1991 Sep;29(9):357-60.

PMID:1937997
Abstract

The extent to which bismuth is absorbed following single and multiple oral administration of basic bismuth nitrate was investigated in healthy male subjects. The blood concentration of bismuth and the amounts excreted in urine and feces were determined. The results show that only a small fraction of the administered bismuth dose given in this form is absorbed. Existing differences in the absorption kinetics between this relatively insoluble bismuth salt and colloidal bismuth citrate are discussed.

摘要

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