Levitz Stuart M
University of Massachusetts Medical School, 364 Plantation Street, LRB317, Worcester, MA 01605, USA.
Cell Host Microbe. 2009 Apr 23;5(4):311-3. doi: 10.1016/j.chom.2009.04.004.
Th17 cells are thought to play a pivotal role in defenses against Candida albicans. van de Veerdonk et al. (2009) investigate components of the fungal cell wall and their cognate receptors on human peripheral blood mononuclear cells (PBMCs) responsible for IL-17 production and find a predominant role for mannan stimulation of the mannose receptor.
Th17细胞被认为在抵御白色念珠菌的防御中起关键作用。范德韦尔登克等人(2009年)研究了真菌细胞壁的成分及其在人外周血单核细胞(PBMCs)上负责产生白细胞介素-17的同源受体,并发现甘露聚糖刺激甘露糖受体起主要作用。